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S-methyl-L-methionine+L-homocysteine->L-methionine

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catalystActivity	[CatalystActivity:1119085] S-adenosylmethionine-homocysteine S-methyltransferase activity of homocysteine S-methyltransferase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26921] EC:2.1.1.10 [DatabaseIdentifier:1148024] RiceCyc:MMUM-RXN
dbId	1120502
displayName	S-methyl-L-methionine+L-homocysteine->L-methionine
eventOf	[Pathway:R-OSA-1119349] S-methylmethionine cycle - Oryza sativa [Pathway:R-OSA-1119400] Methionine biosynthesis II - Oryza sativa
followingEvent	[Reaction:R-OSA-1121231] Methionine S-methyltransferase - Oryza sativa
input	[SimpleEntity:R-ALL-1131040] LHCYS [cytosol] [SimpleEntity:R-ALL-4789070] SMM [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	S-methyl-L-methionine+L-homocysteine->L-methionine MMUM-RXN biochemicalReaction77329 homocysteine S-methyltransferase
orthologousEvent	[Reaction:R-LST-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Lathyrus sativus [Reaction:R-CSI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Citrus sinensis [Reaction:R-JCU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Jatropha curcas [Reaction:R-VFA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Vicia faba var. faba [Reaction:R-AHY-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arachis hypogaea [Reaction:R-SMO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Selaginella moellendorffii [Reaction:R-OLO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza longistaminata [Reaction:R-OGU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza glumaepatula [Reaction:R-PAB-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Picea abies [Reaction:R-MGU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Erythranthe guttata [Reaction:R-CQI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Chenopodium quinoa [Reaction:R-SIN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Sesamum indicum [Reaction:R-NCO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Nymphaea colorata [Reaction:R-FVE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Fragaria vesca [Reaction:R-CCL-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Citrus clementina [Reaction:R-OAU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza australiensis [Reaction:R-ATH-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arabidopsis thaliana [Reaction:R-SHI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Salvia hispanica [Reaction:R-SBI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Sorghum bicolor [Reaction:R-OBA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza barthii [Reaction:R-LSA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Lactuca sativa [Reaction:R-GSO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Glycine soja [Reaction:R-PTI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Populus trichocarpa [Reaction:R-ALY-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arabidopsis lyrata [Reaction:R-OBR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza brachyantha [Reaction:R-CRU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Capsella rubella [Reaction:R-GMA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Glycine max [Reaction:R-OGL-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza glaberrima [Reaction:R-CCA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cajanus cajan [Reaction:R-RCH-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Rosa chinensis [Reaction:R-ADU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arachis duranensis [Reaction:R-BRA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Brassica rapa [Reaction:R-ETE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Eragrostis tef [Reaction:R-FEX-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Fraxinus excelsior (European ash) [Reaction:R-VAN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Vigna angularis [Reaction:R-SIT-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Setaria italica [Reaction:R-HVU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Hordeum vulgare [Reaction:R-BVU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Beta vulgaris [Reaction:R-CSC-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cannabis sativa [Reaction:R-TPR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Trifolium pratense [Reaction:R-PED-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Phyllostachys edulis [Reaction:R-MTR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Medicago truncatula [Reaction:R-ACH-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Actinidia chinensis [Reaction:R-MAC-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Musa acuminata [Reaction:R-ZJA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Zoysia japonica [Reaction:R-MDO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Malus domestica [Reaction:R-BOL-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Brassica oleracea [Reaction:R-TSP-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum spelta subsp. spelta [Reaction:R-LPR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Lolium perenne [Reaction:R-CSA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cucumis sativus [Reaction:R-PHA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Panicum hallii ("FIL2") [Reaction:R-OES-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Olea europaea var. sylvestris [Reaction:R-VUN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Vigna unguiculata [Reaction:R-BNA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Brassica napus [Reaction:R-CAN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Capsicum annuum [Reaction:R-ZMA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Zea mays [Reaction:R-CML-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cucumis melo [Reaction:R-SLY-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Solanum lycopersicum [Reaction:R-CCN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Coffea canephora [Reaction:R-PVE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Pistacia vera [Reaction:R-TTU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum turgidum [Reaction:R-PVU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Phaseolus vulgaris [Reaction:R-HLP-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Humulus lupulus var. lupulus [Reaction:R-DRO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Dioscorea rotundata [Reaction:R-EGR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Eucalyptus grandis [Reaction:R-CCD-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cynara cardunculus var. scolymus [Reaction:R-ECG-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Echinochloa crus-galli [Reaction:R-MPO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Marchantia polymorpha [Reaction:R-BJU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Brassica juncea [Reaction:R-PAV-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Prunus avium [Reaction:R-LAN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Lupinus angustifolius [Reaction:R-PDA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Phoenix dactylifera [Reaction:R-PHH-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Panicum hallii var. hallii ("HAL2") [Reaction:R-QLO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Quercus lobata [Reaction:R-CLA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Citrullus lanatus [Reaction:R-VVN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Vitis vinifera [Reaction:R-AHA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arabidopsis halleri [Reaction:R-NAT-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Nicotiana attenuata [Reaction:R-SCR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Secale cereale [Reaction:R-SVI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Setaria viridis [Reaction:R-TCA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Theobroma cacao [Reaction:R-CBA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Chara braunii [Reaction:R-OGR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza meyeriana var. granulata [Reaction:R-CCP-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Corchorus capsularis [Reaction:R-ACO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Ananas comosus [Reaction:R-ATA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Aegilops tauschii [Reaction:R-OSI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza sativa Indica Group [Reaction:R-ITR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Ipomoea triloba [Reaction:R-NNU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Nelumbo nucifera [Reaction:R-OEU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Olea europaea [Reaction:R-ORU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza rufipogon [Reaction:R-PPE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Prunus persica [Reaction:R-CSK-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cannabis sativa subsp. indica [Reaction:R-PSO-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Papaver somniferum [Reaction:R-FCR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Ficus carica [Reaction:R-PPA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Physcomitrella patens [Reaction:R-TTI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum timopheevii subsp. timopheevii [Reaction:R-HLH-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Humulus lupulus [Reaction:R-OME-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza meridionalis [Reaction:R-PTA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Pinus taeda [Reaction:R-ASA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Avena sativa [Reaction:R-OMI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza minuta [Reaction:R-DEX-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Digitaria exilis [Reaction:R-JRE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Juglans regia [Reaction:R-MES-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Manihot esculenta [Reaction:R-LPE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Leersia perrieri [Reaction:R-TDI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum dicoccoides [Reaction:R-TAE-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum aestivum [Reaction:R-BDI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Brachypodium distachyon [Reaction:R-AIP-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Arachis ipaensis [Reaction:R-ZMY-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Zea mays ver5 [Reaction:R-CST-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Camelina sativa [Reaction:R-VRA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Vigna radiata [Reaction:R-ECU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Eragrostis curvula [Reaction:R-GRA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Gossypium raimondii [Reaction:R-COL-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Corchorus olitorius [Reaction:R-HAN-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Helianthus annuus [Reaction:R-ONI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza nivara [Reaction:R-ATR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Amborella trichopoda [Reaction:R-AUM-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Aegilops umbellulata [Reaction:R-TUR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Triticum urartu [Reaction:R-CAR-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Cicer arietinum [Reaction:R-QSU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Quercus suber [Reaction:R-SSP-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Saccharum spontaneum [Reaction:R-OPU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza punctata [Reaction:R-AOF-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Asparagus officinalis [Reaction:R-PSA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Pisum sativum [Reaction:R-STU-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Solanum tuberosum [Reaction:R-CCI-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Corymbia citriodora [Reaction:R-OOF-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Oryza officinalis [Reaction:R-SPC-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Synechocystis sp. PCC 6803 [Reaction:R-DCA-1120502] S-methyl-L-methionine+L-homocysteine->L-methionine - Daucus carota
output	[SimpleEntity:R-ALL-174390] L-Met [cytosol]
precedingEvent	[Reaction:R-OSA-1120657] cystathionine beta-lyase - Oryza sativa [Reaction:R-OSA-1121231] Methionine S-methyltransferase - Oryza sativa [BlackBoxEvent:R-OSA-4789101] plastid to cytosol transport - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120502
summation	[Summation:4789105] L-homocysteine is converted to L-methionine by enzymatic act...

Referrals

(hasEvent)	[Pathway:R-OSA-1119400] Methionine biosynthesis II - Oryza sativa [Pathway:R-OSA-1119349] S-methylmethionine cycle - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1121231] Methionine S-methyltransferase - Oryza sativa