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homoserine dehydrogenase

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catalystActivity	[CatalystActivity:1118833] homoserine dehydrogenase activity of homoserine dehydrogenase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26543] EC:1.1.1.3 [DatabaseIdentifier:1149397] RiceCyc:HOMOSERDEHYDROG-RXN
dbId	1120265
displayName	homoserine dehydrogenase
eventOf	[Pathway:R-OSA-1119295] Homoserine biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1121450] homoserine kinase - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-1131818] L-aspartate-semialdehyde [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	homoserine dehydrogenase biochemicalReaction93423
orthologousEvent	[Reaction:R-BNA-1120265] homoserine dehydrogenase - Brassica napus [Reaction:R-ITR-1120265] homoserine dehydrogenase - Ipomoea triloba [Reaction:R-SIN-1120265] homoserine dehydrogenase - Sesamum indicum [Reaction:R-CCP-1120265] homoserine dehydrogenase - Corchorus capsularis [Reaction:R-SVI-1120265] homoserine dehydrogenase - Setaria viridis [Reaction:R-AHA-1120265] homoserine dehydrogenase - Arabidopsis halleri [Reaction:R-AHY-1120265] homoserine dehydrogenase - Arachis hypogaea [Reaction:R-ECG-1120265] homoserine dehydrogenase - Echinochloa crus-galli [Reaction:R-ATR-1120265] homoserine dehydrogenase - Amborella trichopoda [Reaction:R-SSP-1120265] homoserine dehydrogenase - Saccharum spontaneum [Reaction:R-SCR-1120265] homoserine dehydrogenase - Secale cereale [Reaction:R-PVU-1120265] homoserine dehydrogenase - Phaseolus vulgaris [Reaction:R-CCR-1120265] homoserine dehydrogenase - Chondrus crispus [Reaction:R-HLP-1120265] homoserine dehydrogenase - Humulus lupulus var. lupulus [Reaction:R-OME-1120265] homoserine dehydrogenase - Oryza meridionalis [Reaction:R-TPR-1120265] homoserine dehydrogenase - Trifolium pratense [Reaction:R-PPA-1120265] homoserine dehydrogenase - Physcomitrella patens [Reaction:R-LAN-1120265] homoserine dehydrogenase - Lupinus angustifolius [Reaction:R-LST-1120265] homoserine dehydrogenase - Lathyrus sativus [Reaction:R-VAN-1120265] homoserine dehydrogenase - Vigna angularis [Reaction:R-CLA-1120265] homoserine dehydrogenase - Citrullus lanatus [Reaction:R-ASA-1120265] homoserine dehydrogenase - Avena sativa [Reaction:R-CAR-1120265] homoserine dehydrogenase - Cicer arietinum [Reaction:R-SLY-1120265] homoserine dehydrogenase - Solanum lycopersicum [Reaction:R-ZJA-1120265] homoserine dehydrogenase - Zoysia japonica [Reaction:R-CSI-1120265] homoserine dehydrogenase - Citrus sinensis [Reaction:R-RCH-1120265] homoserine dehydrogenase - Rosa chinensis [Reaction:R-OBA-1120265] homoserine dehydrogenase - Oryza barthii [Reaction:R-PSO-1120265] homoserine dehydrogenase - Papaver somniferum [Reaction:R-STU-1120265] homoserine dehydrogenase - Solanum tuberosum [Reaction:R-CCL-1120265] homoserine dehydrogenase - Citrus clementina [Reaction:R-ECU-1120265] homoserine dehydrogenase - Eragrostis curvula [Reaction:R-PHH-1120265] homoserine dehydrogenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-TAE-1120265] homoserine dehydrogenase - Triticum aestivum [Reaction:R-CRU-1120265] homoserine dehydrogenase - Capsella rubella [Reaction:R-BDI-1120265] homoserine dehydrogenase - Brachypodium distachyon [Reaction:R-PTA-1120265] homoserine dehydrogenase - Pinus taeda [Reaction:R-ATH-1120265] homoserine dehydrogenase - Arabidopsis thaliana [Reaction:R-PED-1120265] homoserine dehydrogenase - Phyllostachys edulis [Reaction:R-OKA-1120265] homoserine dehydrogenase - Oryza sativa aus subgroup [Reaction:R-CCA-1120265] homoserine dehydrogenase - Cajanus cajan [Reaction:R-VUN-1120265] homoserine dehydrogenase - Vigna unguiculata [Reaction:R-PVE-1120265] homoserine dehydrogenase - Pistacia vera [Reaction:R-TTU-1120265] homoserine dehydrogenase - Triticum turgidum [Reaction:R-OGL-1120265] homoserine dehydrogenase - Oryza glaberrima [Reaction:R-HVU-1120265] homoserine dehydrogenase - Hordeum vulgare [Reaction:R-GSU-1120265] homoserine dehydrogenase - Galdieria sulphuraria [Reaction:R-CCN-1120265] homoserine dehydrogenase - Coffea canephora [Reaction:R-QSU-1120265] homoserine dehydrogenase - Quercus suber [Reaction:R-SHI-1120265] homoserine dehydrogenase - Salvia hispanica [Reaction:R-DEX-1120265] homoserine dehydrogenase - Digitaria exilis [Reaction:R-QLO-1120265] homoserine dehydrogenase - Quercus lobata [Reaction:R-TCA-1120265] homoserine dehydrogenase - Theobroma cacao [Reaction:R-OPU-1120265] homoserine dehydrogenase - Oryza punctata [Reaction:R-SMO-1120265] homoserine dehydrogenase - Selaginella moellendorffii [Reaction:R-DCA-1120265] homoserine dehydrogenase - Daucus carota [Reaction:R-PHA-1120265] homoserine dehydrogenase - Panicum hallii ("FIL2") [Reaction:R-CME-1120265] homoserine dehydrogenase - Cyanidioschyzon merolae [Reaction:R-ONI-1120265] homoserine dehydrogenase - Oryza nivara [Reaction:R-OGU-1120265] homoserine dehydrogenase - Oryza glumaepatula [Reaction:R-BRA-1120265] homoserine dehydrogenase - Brassica rapa [Reaction:R-TTI-1120265] homoserine dehydrogenase - Triticum timopheevii subsp. timopheevii [Reaction:R-HAN-1120265] homoserine dehydrogenase - Helianthus annuus [Reaction:R-PAV-1120265] homoserine dehydrogenase - Prunus avium [Reaction:R-ACO-1120265] homoserine dehydrogenase - Ananas comosus [Reaction:R-CAN-1120265] homoserine dehydrogenase - Capsicum annuum [Reaction:R-SBI-1120265] homoserine dehydrogenase - Sorghum bicolor [Reaction:R-TUR-1120265] homoserine dehydrogenase - Triticum urartu [Reaction:R-ETE-1120265] homoserine dehydrogenase - Eragrostis tef [Reaction:R-VVN-1120265] homoserine dehydrogenase - Vitis vinifera [Reaction:R-TSP-1120265] homoserine dehydrogenase - Triticum spelta subsp. spelta [Reaction:R-MPO-1120265] homoserine dehydrogenase - Marchantia polymorpha [Reaction:R-FVE-1120265] homoserine dehydrogenase - Fragaria vesca [Reaction:R-LPR-1120265] homoserine dehydrogenase - Lolium perenne [Reaction:R-OOF-1120265] homoserine dehydrogenase - Oryza officinalis [Reaction:R-CSA-1120265] homoserine dehydrogenase - Cucumis sativus [Reaction:R-CML-1120265] homoserine dehydrogenase - Cucumis melo [Reaction:R-OLO-1120265] homoserine dehydrogenase - Oryza longistaminata [Reaction:R-ATA-1120265] homoserine dehydrogenase - Aegilops tauschii [Reaction:R-CSC-1120265] homoserine dehydrogenase - Cannabis sativa [Reaction:R-ZMY-1120265] homoserine dehydrogenase - Zea mays ver5 [Reaction:R-CCD-1120265] homoserine dehydrogenase - Cynara cardunculus var. scolymus [Reaction:R-AUM-1120265] homoserine dehydrogenase - Aegilops umbellulata [Reaction:R-BJU-1120265] homoserine dehydrogenase - Brassica juncea [Reaction:R-LSA-1120265] homoserine dehydrogenase - Lactuca sativa [Reaction:R-JRE-1120265] homoserine dehydrogenase - Juglans regia [Reaction:R-GRA-1120265] homoserine dehydrogenase - Gossypium raimondii [Reaction:R-SPC-1120265] homoserine dehydrogenase - Synechocystis sp. PCC 6803 [Reaction:R-CCI-1120265] homoserine dehydrogenase - Corymbia citriodora [Reaction:R-PDA-1120265] homoserine dehydrogenase - Phoenix dactylifera [Reaction:R-EGR-1120265] homoserine dehydrogenase - Eucalyptus grandis [Reaction:R-GMA-1120265] homoserine dehydrogenase - Glycine max [Reaction:R-BOL-1120265] homoserine dehydrogenase - Brassica oleracea [Reaction:R-VRA-1120265] homoserine dehydrogenase - Vigna radiata [Reaction:R-MTR-1120265] homoserine dehydrogenase - Medicago truncatula [Reaction:R-CST-1120265] homoserine dehydrogenase - Camelina sativa [Reaction:R-NAT-1120265] homoserine dehydrogenase - Nicotiana attenuata [Reaction:R-GSO-1120265] homoserine dehydrogenase - Glycine soja [Reaction:R-CQI-1120265] homoserine dehydrogenase - Chenopodium quinoa [Reaction:R-PTI-1120265] homoserine dehydrogenase - Populus trichocarpa [Reaction:R-OES-1120265] homoserine dehydrogenase - Olea europaea var. sylvestris [Reaction:R-COL-1120265] homoserine dehydrogenase - Corchorus olitorius [Reaction:R-FEX-1120265] homoserine dehydrogenase - Fraxinus excelsior (European ash) [Reaction:R-OBR-1120265] homoserine dehydrogenase - Oryza brachyantha [Reaction:R-AIP-1120265] homoserine dehydrogenase - Arachis ipaensis [Reaction:R-TDI-1120265] homoserine dehydrogenase - Triticum dicoccoides [Reaction:R-CRE-1120265] homoserine dehydrogenase - Chlamydomonas reinhardtii [Reaction:R-ACH-1120265] homoserine dehydrogenase - Actinidia chinensis [Reaction:R-MAC-1120265] homoserine dehydrogenase - Musa acuminata [Reaction:R-AOF-1120265] homoserine dehydrogenase - Asparagus officinalis [Reaction:R-CSK-1120265] homoserine dehydrogenase - Cannabis sativa subsp. indica [Reaction:R-DRO-1120265] homoserine dehydrogenase - Dioscorea rotundata [Reaction:R-OMI-1120265] homoserine dehydrogenase - Oryza minuta [Reaction:R-CBA-1120265] homoserine dehydrogenase - Chara braunii [Reaction:R-FCR-1120265] homoserine dehydrogenase - Ficus carica [Reaction:R-ORU-1120265] homoserine dehydrogenase - Oryza rufipogon [Reaction:R-ZMA-1120265] homoserine dehydrogenase - Zea mays [Reaction:R-SIT-1120265] homoserine dehydrogenase - Setaria italica [Reaction:R-LPE-1120265] homoserine dehydrogenase - Leersia perrieri [Reaction:R-PAB-1120265] homoserine dehydrogenase - Picea abies [Reaction:R-OEU-1120265] homoserine dehydrogenase - Olea europaea [Reaction:R-OSI-1120265] homoserine dehydrogenase - Oryza sativa Indica Group [Reaction:R-MGU-1120265] homoserine dehydrogenase - Erythranthe guttata [Reaction:R-JCU-1120265] homoserine dehydrogenase - Jatropha curcas [Reaction:R-MES-1120265] homoserine dehydrogenase - Manihot esculenta [Reaction:R-PPE-1120265] homoserine dehydrogenase - Prunus persica [Reaction:R-OGR-1120265] homoserine dehydrogenase - Oryza meyeriana var. granulata [Reaction:R-ADU-1120265] homoserine dehydrogenase - Arachis duranensis [Reaction:R-HLH-1120265] homoserine dehydrogenase - Humulus lupulus [Reaction:R-MDO-1120265] homoserine dehydrogenase - Malus domestica [Reaction:R-BVU-1120265] homoserine dehydrogenase - Beta vulgaris [Reaction:R-ALY-1120265] homoserine dehydrogenase - Arabidopsis lyrata [Reaction:R-NCO-1120265] homoserine dehydrogenase - Nymphaea colorata [Reaction:R-OAU-1120265] homoserine dehydrogenase - Oryza australiensis [Reaction:R-PSA-1120265] homoserine dehydrogenase - Pisum sativum [Reaction:R-NNU-1120265] homoserine dehydrogenase - Nelumbo nucifera [Reaction:R-VFA-1120265] homoserine dehydrogenase - Vicia faba var. faba
output	[SimpleEntity:R-ALL-1132249] homoserine [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
precedingEvent	[Reaction:R-OSA-1121609] aspartate-semialdehyde dehydrogenase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120265
summation	[Summation:2884003] L-aspartate-semialdehyde is converted to homoserine by enzym...

Referrals

(hasEvent)	[Pathway:R-OSA-1119295] Homoserine biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1121450] homoserine kinase - Oryza sativa