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Proline dehydrogenase

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catalystActivity	[CatalystActivity:1118219] proline dehydrogenase activity of Proline dehydrogenase [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26876] EC:1.5.99.8 [DatabaseIdentifier:1142017] RiceCyc:RXN-821
dbId	1120116
displayName	Proline dehydrogenase
edited	[InstanceEdit:8986575] Gupta, Parul, 2017-04-28
eventOf	[Pathway:R-OSA-1119337] Proline degradation - Oryza sativa [Pathway:R-OSA-1119495] Citrulline biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-5633266] pyrroline 5-carboxylate + H2O + H+> L-glutamate gamma-semialdehyde - Oryza sativa [Reaction:R-OSA-1119633] 1-pyrroline-5-carboxylate dehydrogenase - Oryza sativa [Reaction:R-OSA-1120680] L-glutamate gamma-semialdehyde->H2O+pyrroline 5-carboxylate - Oryza sativa
input	[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix] [SimpleEntity:R-ALL-379717] L-Pro [mitochondrial matrix]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Proline dehydrogenase biochemicalReaction78980
orthologousEvent	[Reaction:R-ETE-1120116] Proline dehydrogenase - Eragrostis tef [Reaction:R-AIP-1120116] Proline dehydrogenase - Arachis ipaensis [Reaction:R-ORU-1120116] Proline dehydrogenase - Oryza rufipogon [Reaction:R-CSA-1120116] Proline dehydrogenase - Cucumis sativus [Reaction:R-QSU-1120116] Proline dehydrogenase - Quercus suber [Reaction:R-ASA-1120116] Proline dehydrogenase - Avena sativa [Reaction:R-TCA-1120116] Proline dehydrogenase - Theobroma cacao [Reaction:R-FEX-1120116] Proline dehydrogenase - Fraxinus excelsior (European ash) [Reaction:R-TDI-1120116] Proline dehydrogenase - Triticum dicoccoides [Reaction:R-PHA-1120116] Proline dehydrogenase - Panicum hallii ("FIL2") [Reaction:R-OGL-1120116] Proline dehydrogenase - Oryza glaberrima [Reaction:R-DEX-1120116] Proline dehydrogenase - Digitaria exilis [Reaction:R-NCO-1120116] Proline dehydrogenase - Nymphaea colorata [Reaction:R-ACO-1120116] Proline dehydrogenase - Ananas comosus [Reaction:R-PSO-1120116] Proline dehydrogenase - Papaver somniferum [Reaction:R-DRO-1120116] Proline dehydrogenase - Dioscorea rotundata [Reaction:R-NNU-1120116] Proline dehydrogenase - Nelumbo nucifera [Reaction:R-CRE-1120116] Proline dehydrogenase - Chlamydomonas reinhardtii [Reaction:R-AOF-1120116] Proline dehydrogenase - Asparagus officinalis [Reaction:R-SLY-1120116] Proline dehydrogenase - Solanum lycopersicum [Reaction:R-BVU-1120116] Proline dehydrogenase - Beta vulgaris [Reaction:R-NAT-1120116] Proline dehydrogenase - Nicotiana attenuata [Reaction:R-ITR-1120116] Proline dehydrogenase - Ipomoea triloba [Reaction:R-CAN-1120116] Proline dehydrogenase - Capsicum annuum [Reaction:R-AUM-1120116] Proline dehydrogenase - Aegilops umbellulata [Reaction:R-CRU-1120116] Proline dehydrogenase - Capsella rubella [Reaction:R-FVE-1120116] Proline dehydrogenase - Fragaria vesca [Reaction:R-ATA-1120116] Proline dehydrogenase - Aegilops tauschii [Reaction:R-PAV-1120116] Proline dehydrogenase - Prunus avium [Reaction:R-OOF-1120116] Proline dehydrogenase - Oryza officinalis [Reaction:R-CCA-1120116] Proline dehydrogenase - Cajanus cajan [Reaction:R-HLH-1120116] Proline dehydrogenase - Humulus lupulus [Reaction:R-SIT-1120116] Proline dehydrogenase - Setaria italica [Reaction:R-CML-1120116] Proline dehydrogenase - Cucumis melo [Reaction:R-CCD-1120116] Proline dehydrogenase - Cynara cardunculus var. scolymus [Reaction:R-OBA-1120116] Proline dehydrogenase - Oryza barthii [Reaction:R-TTU-1120116] Proline dehydrogenase - Triticum turgidum [Reaction:R-GSO-1120116] Proline dehydrogenase - Glycine soja [Reaction:R-HAN-1120116] Proline dehydrogenase - Helianthus annuus [Reaction:R-COL-1120116] Proline dehydrogenase - Corchorus olitorius [Reaction:R-SHI-1120116] Proline dehydrogenase - Salvia hispanica [Reaction:R-TAE-1120116] Proline dehydrogenase - Triticum aestivum [Reaction:R-HVU-1120116] Proline dehydrogenase - Hordeum vulgare [Reaction:R-CSC-1120116] Proline dehydrogenase - Cannabis sativa [Reaction:R-PPA-1120116] Proline dehydrogenase - Physcomitrella patens [Reaction:R-VRA-1120116] Proline dehydrogenase - Vigna radiata [Reaction:R-SMO-1120116] Proline dehydrogenase - Selaginella moellendorffii [Reaction:R-CLA-1120116] Proline dehydrogenase - Citrullus lanatus [Reaction:R-SCR-1120116] Proline dehydrogenase - Secale cereale [Reaction:R-CSI-1120116] Proline dehydrogenase - Citrus sinensis [Reaction:R-OPU-1120116] Proline dehydrogenase - Oryza punctata [Reaction:R-MAC-1120116] Proline dehydrogenase - Musa acuminata [Reaction:R-JRE-1120116] Proline dehydrogenase - Juglans regia [Reaction:R-VFA-1120116] Proline dehydrogenase - Vicia faba var. faba [Reaction:R-BDI-1120116] Proline dehydrogenase - Brachypodium distachyon [Reaction:R-CSK-1120116] Proline dehydrogenase - Cannabis sativa subsp. indica [Reaction:R-PTA-1120116] Proline dehydrogenase - Pinus taeda [Reaction:R-TTI-1120116] Proline dehydrogenase - Triticum timopheevii subsp. timopheevii [Reaction:R-LPE-1120116] Proline dehydrogenase - Leersia perrieri [Reaction:R-EGR-1120116] Proline dehydrogenase - Eucalyptus grandis [Reaction:R-PDA-1120116] Proline dehydrogenase - Phoenix dactylifera [Reaction:R-TPR-1120116] Proline dehydrogenase - Trifolium pratense [Reaction:R-ECG-1120116] Proline dehydrogenase - Echinochloa crus-galli [Reaction:R-GRA-1120116] Proline dehydrogenase - Gossypium raimondii [Reaction:R-RCH-1120116] Proline dehydrogenase - Rosa chinensis [Reaction:R-CQI-1120116] Proline dehydrogenase - Chenopodium quinoa [Reaction:R-CCN-1120116] Proline dehydrogenase - Coffea canephora [Reaction:R-LAN-1120116] Proline dehydrogenase - Lupinus angustifolius [Reaction:R-HLP-1120116] Proline dehydrogenase - Humulus lupulus var. lupulus [Reaction:R-MTR-1120116] Proline dehydrogenase - Medicago truncatula [Reaction:R-PVE-1120116] Proline dehydrogenase - Pistacia vera [Reaction:R-PSA-1120116] Proline dehydrogenase - Pisum sativum [Reaction:R-OBR-1120116] Proline dehydrogenase - Oryza brachyantha [Reaction:R-SIN-1120116] Proline dehydrogenase - Sesamum indicum [Reaction:R-CCL-1120116] Proline dehydrogenase - Citrus clementina [Reaction:R-CCI-1120116] Proline dehydrogenase - Corymbia citriodora [Reaction:R-ZMA-1120116] Proline dehydrogenase - Zea mays [Reaction:R-CST-1120116] Proline dehydrogenase - Camelina sativa [Reaction:R-PTI-1120116] Proline dehydrogenase - Populus trichocarpa [Reaction:R-GMA-1120116] Proline dehydrogenase - Glycine max [Reaction:R-PVU-1120116] Proline dehydrogenase - Phaseolus vulgaris [Reaction:R-TSP-1120116] Proline dehydrogenase - Triticum spelta subsp. spelta [Reaction:R-SBI-1120116] Proline dehydrogenase - Sorghum bicolor [Reaction:R-AHY-1120116] Proline dehydrogenase - Arachis hypogaea [Reaction:R-CCP-1120116] Proline dehydrogenase - Corchorus capsularis [Reaction:R-MES-1120116] Proline dehydrogenase - Manihot esculenta [Reaction:R-STU-1120116] Proline dehydrogenase - Solanum tuberosum [Reaction:R-SVI-1120116] Proline dehydrogenase - Setaria viridis [Reaction:R-TUR-1120116] Proline dehydrogenase - Triticum urartu [Reaction:R-VUN-1120116] Proline dehydrogenase - Vigna unguiculata [Reaction:R-OGU-1120116] Proline dehydrogenase - Oryza glumaepatula [Reaction:R-ZMY-1120116] Proline dehydrogenase - Zea mays ver5 [Reaction:R-QLO-1120116] Proline dehydrogenase - Quercus lobata [Reaction:R-LSA-1120116] Proline dehydrogenase - Lactuca sativa [Reaction:R-ADU-1120116] Proline dehydrogenase - Arachis duranensis [Reaction:R-VVN-1120116] Proline dehydrogenase - Vitis vinifera [Reaction:R-PED-1120116] Proline dehydrogenase - Phyllostachys edulis [Reaction:R-OSI-1120116] Proline dehydrogenase - Oryza sativa Indica Group [Reaction:R-LPR-1120116] Proline dehydrogenase - Lolium perenne [Reaction:R-MGU-1120116] Proline dehydrogenase - Erythranthe guttata [Reaction:R-LST-1120116] Proline dehydrogenase - Lathyrus sativus [Reaction:R-GSU-1120116] Proline dehydrogenase - Galdieria sulphuraria [Reaction:R-VAN-1120116] Proline dehydrogenase - Vigna angularis [Reaction:R-MDO-1120116] Proline dehydrogenase - Malus domestica [Reaction:R-ATR-1120116] Proline dehydrogenase - Amborella trichopoda [Reaction:R-ECU-1120116] Proline dehydrogenase - Eragrostis curvula [Reaction:R-DCA-1120116] Proline dehydrogenase - Daucus carota [Reaction:R-MPO-1120116] Proline dehydrogenase - Marchantia polymorpha [Reaction:R-PAB-1120116] Proline dehydrogenase - Picea abies [Reaction:R-PHH-1120116] Proline dehydrogenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-PPE-1120116] Proline dehydrogenase - Prunus persica [Reaction:R-OME-1120116] Proline dehydrogenase - Oryza meridionalis [Reaction:R-ZJA-1120116] Proline dehydrogenase - Zoysia japonica [Reaction:R-CAR-1120116] Proline dehydrogenase - Cicer arietinum [Reaction:R-ACH-1120116] Proline dehydrogenase - Actinidia chinensis [Reaction:R-ONI-1120116] Proline dehydrogenase - Oryza nivara
output	[SimpleEntity:R-ALL-113590] 1PYR-5COOH [mitochondrial matrix] [SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix]
reviewed	[InstanceEdit:8986575] Gupta, Parul, 2017-04-28
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120116
summation	[Summation:9026270] EC 1.5.99.8 for the enzyme proline dehydrogenase has been tr...

Referrals

(hasEvent)	[Pathway:R-OSA-1119495] Citrulline biosynthesis - Oryza sativa [Pathway:R-OSA-1119337] Proline degradation - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-5633266] pyrroline 5-carboxylate + H2O + H+> L-glutamate gamma-semialdehyde - Oryza sativa [Reaction:R-OSA-1120680] L-glutamate gamma-semialdehyde->H2O+pyrroline 5-carboxylate - Oryza sativa [Reaction:R-OSA-1119633] 1-pyrroline-5-carboxylate dehydrogenase - Oryza sativa