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Leucocyanidin oxygenase

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catalystActivity	[CatalystActivity:1118467] 2-oxoglutarate-dependent dioxygenase activity of leucoanthocyanidin dioxygenase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:71828] EC:1.14.11.- [DatabaseIdentifier:1135911] RiceCyc:RXN-602
dbId	1119807
displayName	Leucocyanidin oxygenase
eventOf	[Pathway:R-OSA-1119440] Anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside) - Oryza sativa
followingEvent	[Reaction:R-OSA-1121636] UDP-D-glucose+cyanidin->UDP+cyanidin-3-O-beta-D-glucoside - Oryza sativa
input	[SimpleEntity:R-ALL-29406] 2OG [cytosol] [SimpleEntity:R-ALL-1131535] leucocyanidin [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Leucocyanidin oxygenase Anthocyanidin synthase Leucoanthocyanidin dioxygenase biochemicalReaction87048
orthologousEvent	[Reaction:R-OES-1119807] Leucocyanidin oxygenase - Olea europaea var. sylvestris [Reaction:R-QLO-1119807] Leucocyanidin oxygenase - Quercus lobata [Reaction:R-OSI-1119807] Leucocyanidin oxygenase - Oryza sativa Indica Group [Reaction:R-LPR-1119807] Leucocyanidin oxygenase - Lolium perenne [Reaction:R-HVU-1119807] Leucocyanidin oxygenase - Hordeum vulgare [Reaction:R-AHA-1119807] Leucocyanidin oxygenase - Arabidopsis halleri [Reaction:R-AIP-1119807] Leucocyanidin oxygenase - Arachis ipaensis [Reaction:R-MTR-1119807] Leucocyanidin oxygenase - Medicago truncatula [Reaction:R-PSA-1119807] Leucocyanidin oxygenase - Pisum sativum [Reaction:R-LSA-1119807] Leucocyanidin oxygenase - Lactuca sativa [Reaction:R-HAN-1119807] Leucocyanidin oxygenase - Helianthus annuus [Reaction:R-CCL-1119807] Leucocyanidin oxygenase - Citrus clementina [Reaction:R-PED-1119807] Leucocyanidin oxygenase - Phyllostachys edulis [Reaction:R-QSU-1119807] Leucocyanidin oxygenase - Quercus suber [Reaction:R-ECU-1119807] Leucocyanidin oxygenase - Eragrostis curvula [Reaction:R-CCA-1119807] Leucocyanidin oxygenase - Cajanus cajan [Reaction:R-GSO-1119807] Leucocyanidin oxygenase - Glycine soja [Reaction:R-PDA-1119807] Leucocyanidin oxygenase - Phoenix dactylifera [Reaction:R-SBI-1119807] Leucocyanidin oxygenase - Sorghum bicolor [Reaction:R-PHH-1119807] Leucocyanidin oxygenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-PTA-1119807] Leucocyanidin oxygenase - Pinus taeda [Reaction:R-COL-1119807] Leucocyanidin oxygenase - Corchorus olitorius [Reaction:R-TSP-1119807] Leucocyanidin oxygenase - Triticum spelta subsp. spelta [Reaction:R-OEU-1119807] Leucocyanidin oxygenase - Olea europaea [Reaction:R-OBA-1119807] Leucocyanidin oxygenase - Oryza barthii [Reaction:R-GMA-1119807] Leucocyanidin oxygenase - Glycine max [Reaction:R-ZJA-1119807] Leucocyanidin oxygenase - Zoysia japonica [Reaction:R-LST-1119807] Leucocyanidin oxygenase - Lathyrus sativus [Reaction:R-PPE-1119807] Leucocyanidin oxygenase - Prunus persica [Reaction:R-CLA-1119807] Leucocyanidin oxygenase - Citrullus lanatus [Reaction:R-SVI-1119807] Leucocyanidin oxygenase - Setaria viridis [Reaction:R-ZMA-1119807] Leucocyanidin oxygenase - Zea mays [Reaction:R-BNA-1119807] Leucocyanidin oxygenase - Brassica napus [Reaction:R-EGR-1119807] Leucocyanidin oxygenase - Eucalyptus grandis [Reaction:R-VAN-1119807] Leucocyanidin oxygenase - Vigna angularis [Reaction:R-CRU-1119807] Leucocyanidin oxygenase - Capsella rubella [Reaction:R-LPE-1119807] Leucocyanidin oxygenase - Leersia perrieri [Reaction:R-NAT-1119807] Leucocyanidin oxygenase - Nicotiana attenuata [Reaction:R-PVU-1119807] Leucocyanidin oxygenase - Phaseolus vulgaris [Reaction:R-RCH-1119807] Leucocyanidin oxygenase - Rosa chinensis [Reaction:R-TDI-1119807] Leucocyanidin oxygenase - Triticum dicoccoides [Reaction:R-ATH-1119807] Leucocyanidin oxygenase - Arabidopsis thaliana [Reaction:R-CAR-1119807] Leucocyanidin oxygenase - Cicer arietinum [Reaction:R-ALY-1119807] Leucocyanidin oxygenase - Arabidopsis lyrata [Reaction:R-TCA-1119807] Leucocyanidin oxygenase - Theobroma cacao [Reaction:R-OGU-1119807] Leucocyanidin oxygenase - Oryza glumaepatula [Reaction:R-HLP-1119807] Leucocyanidin oxygenase - Humulus lupulus var. lupulus [Reaction:R-FCR-1119807] Leucocyanidin oxygenase - Ficus carica [Reaction:R-BOL-1119807] Leucocyanidin oxygenase - Brassica oleracea [Reaction:R-VUN-1119807] Leucocyanidin oxygenase - Vigna unguiculata [Reaction:R-TPR-1119807] Leucocyanidin oxygenase - Trifolium pratense [Reaction:R-OME-1119807] Leucocyanidin oxygenase - Oryza meridionalis [Reaction:R-ACH-1119807] Leucocyanidin oxygenase - Actinidia chinensis [Reaction:R-MDO-1119807] Leucocyanidin oxygenase - Malus domestica [Reaction:R-PAB-1119807] Leucocyanidin oxygenase - Picea abies [Reaction:R-TTI-1119807] Leucocyanidin oxygenase - Triticum timopheevii subsp. timopheevii [Reaction:R-NNU-1119807] Leucocyanidin oxygenase - Nelumbo nucifera [Reaction:R-CSC-1119807] Leucocyanidin oxygenase - Cannabis sativa [Reaction:R-ADU-1119807] Leucocyanidin oxygenase - Arachis duranensis [Reaction:R-AUM-1119807] Leucocyanidin oxygenase - Aegilops umbellulata [Reaction:R-SIN-1119807] Leucocyanidin oxygenase - Sesamum indicum [Reaction:R-CSK-1119807] Leucocyanidin oxygenase - Cannabis sativa subsp. indica [Reaction:R-VFA-1119807] Leucocyanidin oxygenase - Vicia faba var. faba [Reaction:R-OOF-1119807] Leucocyanidin oxygenase - Oryza officinalis [Reaction:R-DRO-1119807] Leucocyanidin oxygenase - Dioscorea rotundata [Reaction:R-GRA-1119807] Leucocyanidin oxygenase - Gossypium raimondii [Reaction:R-OAU-1119807] Leucocyanidin oxygenase - Oryza australiensis [Reaction:R-ATA-1119807] Leucocyanidin oxygenase - Aegilops tauschii [Reaction:R-JCU-1119807] Leucocyanidin oxygenase - Jatropha curcas [Reaction:R-CAN-1119807] Leucocyanidin oxygenase - Capsicum annuum [Reaction:R-SHI-1119807] Leucocyanidin oxygenase - Salvia hispanica [Reaction:R-FVE-1119807] Leucocyanidin oxygenase - Fragaria vesca [Reaction:R-MAC-1119807] Leucocyanidin oxygenase - Musa acuminata [Reaction:R-ONI-1119807] Leucocyanidin oxygenase - Oryza nivara [Reaction:R-LAN-1119807] Leucocyanidin oxygenase - Lupinus angustifolius [Reaction:R-BJU-1119807] Leucocyanidin oxygenase - Brassica juncea [Reaction:R-VVN-1119807] Leucocyanidin oxygenase - Vitis vinifera [Reaction:R-TTU-1119807] Leucocyanidin oxygenase - Triticum turgidum [Reaction:R-DCA-1119807] Leucocyanidin oxygenase - Daucus carota [Reaction:R-ASA-1119807] Leucocyanidin oxygenase - Avena sativa [Reaction:R-PTI-1119807] Leucocyanidin oxygenase - Populus trichocarpa [Reaction:R-ETE-1119807] Leucocyanidin oxygenase - Eragrostis tef [Reaction:R-SIT-1119807] Leucocyanidin oxygenase - Setaria italica [Reaction:R-PHA-1119807] Leucocyanidin oxygenase - Panicum hallii ("FIL2") [Reaction:R-OGR-1119807] Leucocyanidin oxygenase - Oryza meyeriana var. granulata [Reaction:R-CST-1119807] Leucocyanidin oxygenase - Camelina sativa [Reaction:R-OPU-1119807] Leucocyanidin oxygenase - Oryza punctata [Reaction:R-CSI-1119807] Leucocyanidin oxygenase - Citrus sinensis [Reaction:R-SLY-1119807] Leucocyanidin oxygenase - Solanum lycopersicum [Reaction:R-PVE-1119807] Leucocyanidin oxygenase - Pistacia vera [Reaction:R-DEX-1119807] Leucocyanidin oxygenase - Digitaria exilis [Reaction:R-VRA-1119807] Leucocyanidin oxygenase - Vigna radiata [Reaction:R-HLH-1119807] Leucocyanidin oxygenase - Humulus lupulus [Reaction:R-ITR-1119807] Leucocyanidin oxygenase - Ipomoea triloba [Reaction:R-TAE-1119807] Leucocyanidin oxygenase - Triticum aestivum [Reaction:R-ZMY-1119807] Leucocyanidin oxygenase - Zea mays ver5 [Reaction:R-MGU-1119807] Leucocyanidin oxygenase - Erythranthe guttata [Reaction:R-NCO-1119807] Leucocyanidin oxygenase - Nymphaea colorata [Reaction:R-AHY-1119807] Leucocyanidin oxygenase - Arachis hypogaea [Reaction:R-PSO-1119807] Leucocyanidin oxygenase - Papaver somniferum [Reaction:R-BRA-1119807] Leucocyanidin oxygenase - Brassica rapa [Reaction:R-OMI-1119807] Leucocyanidin oxygenase - Oryza minuta [Reaction:R-FEX-1119807] Leucocyanidin oxygenase - Fraxinus excelsior (European ash) [Reaction:R-PAV-1119807] Leucocyanidin oxygenase - Prunus avium [Reaction:R-SCR-1119807] Leucocyanidin oxygenase - Secale cereale [Reaction:R-OGL-1119807] Leucocyanidin oxygenase - Oryza glaberrima [Reaction:R-JRE-1119807] Leucocyanidin oxygenase - Juglans regia [Reaction:R-MES-1119807] Leucocyanidin oxygenase - Manihot esculenta
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-1130817] cyanidin [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29434] SUCCA [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1119807
summation	[Summation:2850406] Leucocyanidin is converted into cyanidin by enzymatic activi...

Referrals

(hasEvent)	[Pathway:R-OSA-1119440] Anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside) - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1121636] UDP-D-glucose+cyanidin->UDP+cyanidin-3-O-beta-D-glucoside - Oryza sativa

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