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Conversion of MACR-CoA to 3-hydroxy-isobutyryl-CoA

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catalystActivity	[CatalystActivity:10771753] enoyl-CoA hydratase activity of enoyl-CoA hydratase [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10764017] Elser, Justin, 2025-03-25
dbId	10771755
displayName	Conversion of MACR-CoA to 3-hydroxy-isobutyryl-CoA
eventOf	[Pathway:R-NAT-1119479] Valine degradation - Nicotiana attenuata
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-NAT-9611885] Conversion of 3-hydroxy-isobutyryl-CoA to 3-hydroxy-isobutyrate - Nicotiana attenuata
inferredFrom	[Reaction:R-OSA-9611868] Conversion of MACR-CoA to 3-hydroxy-isobutyryl-CoA - Oryza sativa
input	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-70858] MACR-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
name	Conversion of MACR-CoA to 3-hydroxy-isobutyryl-CoA
output	[SimpleEntity:R-ALL-9611893] 3-hydroxy-isobutyryl-CoA [mitochondrial matrix]
precedingEvent	[Reaction:R-NAT-9611898] Conversion of ISB-CoA to MACR-CoA - Nicotiana attenuata
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9030188] Nicotiana attenuata
stId	R-NAT-9611868
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-NAT-1119479] Valine degradation - Nicotiana attenuata
(precedingEvent)	[Reaction:R-NAT-9611885] Conversion of 3-hydroxy-isobutyryl-CoA to 3-hydroxy-isobutyrate - Nicotiana attenuata
(inferredTo)	[Reaction:R-OSA-9611868] Conversion of MACR-CoA to 3-hydroxy-isobutyryl-CoA - Oryza sativa