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4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A

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catalystActivity	[CatalystActivity:11126620] cinnamoyl-CoA reductase activity of cinnamoyl-CoA reductase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11125022] Elser, Justin, 2025-03-26
dbId	11126622
displayName	4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A
eventOf	[Pathway:R-LSA-1119316] Phenylpropanoid biosynthesis - Lactuca sativa
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-LSA-1121401] coumaraldehyde+NADPH->coumaryl-alcohol+NADP+ - Lactuca sativa
inferredFrom	[Reaction:R-OSA-1120189] 4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A - Oryza sativa
input	[SimpleEntity:R-ALL-1130740] 4-coumaroyl-CoA [cytosol] [SimpleEntity:R-ALL-1131945] coumaroyl-CoA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
name	4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A RXN-1101 biochemicalReaction82910
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1132366] coumaraldehyde [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9764170] Lactuca sativa
stId	R-LSA-1120189
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-LSA-1119316] Phenylpropanoid biosynthesis - Lactuca sativa
(precedingEvent)	[Reaction:R-LSA-1121401] coumaraldehyde+NADPH->coumaryl-alcohol+NADP+ - Lactuca sativa
(inferredTo)	[Reaction:R-OSA-1120189] 4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A - Oryza sativa

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