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Synthesis of 20 nucelotide primer at origin

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catalystActivity	[CatalystActivity:11323609] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11315319] Elser, Justin, 2025-03-26
dbId	11323611
displayName	Synthesis of 20 nucelotide primer at origin
eventOf	[Pathway:R-LPR-9675824] DNA replication Initiation - Lolium perenne
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-LPR-9675841] Binding of RFC - Lolium perenne
inferredFrom	[Reaction:R-OSA-9675791] Synthesis of 20 nucelotide primer at origin - Oryza sativa
input	[SimpleEntity:R-ALL-29604] dATP [nucleoplasm] [SimpleEntity:R-ALL-30185] dCTP [nucleoplasm] [SimpleEntity:R-ALL-29892] dGTP [nucleoplasm] [SimpleEntity:R-ALL-30187] dTTP [nucleoplasm] [Complex:R-LPR-9675881] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm]
isInDisease	false
isInferred	true
name	Synthesis of 20 nucelotide primer at origin
output	[Complex:R-LPR-9675832] RNA primer:origin duplex:DNA primer [nucleoplasm]
precedingEvent	[Reaction:R-LPR-9675867] Synthesis of 6-10 nucelotide RNA primer at origin - Lolium perenne
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9823393] Lolium perenne
stId	R-LPR-9675791
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(precedingEvent)	[Reaction:R-LPR-9675841] Binding of RFC - Lolium perenne
(hasEvent)	[Pathway:R-LPR-9675824] DNA replication Initiation - Lolium perenne
(inferredTo)	[Reaction:R-OSA-9675791] Synthesis of 20 nucelotide primer at origin - Oryza sativa