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catalystActivity	[CatalystActivity:10129207] glutamate decarboxylase activity of GAD [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10122017] Elser, Justin, 2025-03-24
dbId	10129209
displayName	Formation of GABA
eventOf	[Pathway:R-HLP-1119458] Glutamate degradation - Humulus lupulus var. lupulus
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-HLP-1120519] Formation of succinic semialdehyde - Humulus lupulus var. lupulus
inferredFrom	[Reaction:R-OSA-1121221] Formation of GABA - Oryza sativa
input	[SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	true
name	Formation of GABA Glutamate decarboxylase biochemicalReaction14657
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-352011] GABA [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9659299] Humulus lupulus var. lupulus
stId	R-HLP-1121221
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

(hasEvent)	[Pathway:R-HLP-1119458] Glutamate degradation - Humulus lupulus var. lupulus
(precedingEvent)	[Reaction:R-HLP-1120519] Formation of succinic semialdehyde - Humulus lupulus var. lupulus
(inferredTo)	[Reaction:R-OSA-1121221] Formation of GABA - Oryza sativa