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4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O

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catalystActivity	[CatalystActivity:11454462] C-4 methylsterol oxidase activity of Methylsterol monooxygenase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11454023] Elser, Justin, 2025-03-26
dbId	11454526
displayName	4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O
eventOf	[Pathway:R-GSO-1119439] Cholesterol biosynthesis III (via desmosterol) - Glycine soja [Pathway:R-GSO-1119559] Cholesterol biosynthesis I - Glycine soja
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
inferredFrom	[Reaction:R-OSA-1119749] 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa
input	[SimpleEntity:R-ALL-1130530] 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
name	4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O RXN66-312 biochemicalReaction85460
output	[SimpleEntity:R-ALL-1130851] 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
precedingEvent	[Reaction:R-GSO-1121133] 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Glycine soja
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9933483] Glycine soja
stId	R-GSO-1119749
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-GSO-1119439] Cholesterol biosynthesis III (via desmosterol) - Glycine soja [Pathway:R-GSO-1119559] Cholesterol biosynthesis I - Glycine soja
(inferredTo)	[Reaction:R-OSA-1119749] 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa

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