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catalystActivity	[CatalystActivity:11450936] cyclin-dependent protein serine/threonine kinase activity of Phospho-CDKA:CycD [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11440306] Elser, Justin, 2025-03-26
dbId	11450938
displayName	Activation of E2F:DP complex
eventOf	[Pathway:R-FEX-9640887] G1/S transition - Fraxinus excelsior (European ash)
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
inferredFrom	[Reaction:R-OSA-9640851] Activation of E2F:DP complex - Oryza sativa
input	[Complex:R-FEX-9640893] DP:E2F:RBR [nucleoplasm]
isInDisease	false
isInferred	true
name	Activation of E2F:DP complex Phosphorylation of Rb protein
output	[Complex:R-FEX-9640879] DP:E2F [nucleoplasm] [EntityWithAccessionedSequence:R-FEX-9640885] phospho-FRAEX38873_v2_000250600 [nucleoplasm]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9933481] Fraxinus excelsior (European ash)
stId	R-FEX-9640851
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

(hasEvent)	[Pathway:R-FEX-9640887] G1/S transition - Fraxinus excelsior (European ash)
(inferredTo)	[Reaction:R-OSA-9640851] Activation of E2F:DP complex - Oryza sativa