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catalystActivity	[CatalystActivity:11444934] glutamate decarboxylase activity of GAD [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11440306] Elser, Justin, 2025-03-26
dbId	11444936
displayName	Formation of GABA
eventOf	[Pathway:R-FEX-1119458] Glutamate degradation - Fraxinus excelsior (European ash)
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-FEX-1120519] Formation of succinic semialdehyde - Fraxinus excelsior (European ash)
inferredFrom	[Reaction:R-OSA-1121221] Formation of GABA - Oryza sativa
input	[SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	true
name	Formation of GABA Glutamate decarboxylase biochemicalReaction14657
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-352011] GABA [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9933481] Fraxinus excelsior (European ash)
stId	R-FEX-1121221
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

(hasEvent)	[Pathway:R-FEX-1119458] Glutamate degradation - Fraxinus excelsior (European ash)
(precedingEvent)	[Reaction:R-FEX-1120519] Formation of succinic semialdehyde - Fraxinus excelsior (European ash)
(inferredTo)	[Reaction:R-OSA-1121221] Formation of GABA - Oryza sativa