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L-tryptophan+NADPH+O2->indole-3-acetaldoxime+CO2+NADP++H2O

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catalystActivity	[CatalystActivity:10189729] tryptophan N-monooxygenase activity of Tryptophan monooxygenase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10184436] Elser, Justin, 2025-03-24
dbId	10189731
displayName	L-tryptophan+NADPH+O2->indole-3-acetaldoxime+CO2+NADP++H2O
eventOf	[Pathway:R-ETE-1119486] IAA biosynthesis I - Eragrostis tef
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-ETE-1120717] Indole-3-acetaldehyde oxidase - Eragrostis tef [Reaction:R-ETE-1119651] indole-3-acetaldoxime->indole-3-acetonitrile+H2O - Eragrostis tef
inferredFrom	[Reaction:R-OSA-1120968] L-tryptophan+NADPH+O2->indole-3-acetaldoxime+CO2+NADP++H2O - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29500] L-Trp [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
name	L-tryptophan+NADPH+O2->indole-3-acetaldoxime+CO2+NADP++H2O RXN-1402 biochemicalReaction86197
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1130702] indole-3-acetaldoxime [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9659258] Eragrostis tef
stId	R-ETE-1120968
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-ETE-1119486] IAA biosynthesis I - Eragrostis tef
(precedingEvent)	[Reaction:R-ETE-1120717] Indole-3-acetaldehyde oxidase - Eragrostis tef [Reaction:R-ETE-1119651] indole-3-acetaldoxime->indole-3-acetonitrile+H2O - Eragrostis tef
(inferredTo)	[Reaction:R-OSA-1120968] L-tryptophan+NADPH+O2->indole-3-acetaldoxime+CO2+NADP++H2O - Oryza sativa

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