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4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O

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compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9986734] Elser, Justin, 2025-03-24
dbId	9991242
displayName	4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O
eventOf	[Pathway:R-ECU-1119439] Cholesterol biosynthesis III (via desmosterol) - Eragrostis curvula [Pathway:R-ECU-1119559] Cholesterol biosynthesis I - Eragrostis curvula
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-ECU-1120443] 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Eragrostis curvula
inferredFrom	[Reaction:R-OSA-1121309] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa
input	[SimpleEntity:R-ALL-1131017] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
name	4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O RXN66-316 biochemicalReaction85426
output	[SimpleEntity:R-ALL-1130738] 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] 2 × [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
precedingEvent	[Reaction:R-ECU-1121120] 4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Eragrostis curvula
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9689261] Eragrostis curvula
stId	R-ECU-1121309
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-ECU-1119439] Cholesterol biosynthesis III (via desmosterol) - Eragrostis curvula [Pathway:R-ECU-1119559] Cholesterol biosynthesis I - Eragrostis curvula
(precedingEvent)	[Reaction:R-ECU-1120443] 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Eragrostis curvula
(inferredTo)	[Reaction:R-OSA-1121309] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa

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