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UDP-N-acetylmuramoylalanine--D-glutamate ligase

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catalystActivity	[CatalystActivity:10077998] UDP-N-acetylmuramoylalanine-D-glutamate ligase activity of Mur ligase family protein (LOC_OS10G40130.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10074907] Elser, Justin, 2025-03-24
dbId	10078062
displayName	UDP-N-acetylmuramoylalanine--D-glutamate ligase
eventOf	[Pathway:R-CSK-1119436] Peptidoglycan biosynthesis I - Cannabis sativa subsp. indica
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-CSK-1120870] UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase - Cannabis sativa subsp. indica
inferredFrom	[Reaction:R-OSA-1120897] UDP-N-acetylmuramoylalanine--D-glutamate ligase - Oryza sativa
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-1132405] D-Glu [cytosol] [SimpleEntity:R-ALL-1131294] UDP-N-acetylmuramoyl-L-alanine [cytosol]
isInDisease	false
isInferred	true
name	UDP-N-acetylmuramoylalanine--D-glutamate ligase D-glutamate ligase D-glutamate-adding enzyme UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase biochemicalReaction6596
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-1131663] UDP-N-acetylmuramoyl-L-alanyl-D-glutamate [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9659007] Cannabis sativa subsp. indica
stId	R-CSK-1120897
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-CSK-1119436] Peptidoglycan biosynthesis I - Cannabis sativa subsp. indica
(precedingEvent)	[Reaction:R-CSK-1120870] UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase - Cannabis sativa subsp. indica
(inferredTo)	[Reaction:R-OSA-1120897] UDP-N-acetylmuramoylalanine--D-glutamate ligase - Oryza sativa

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