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succinyl-CoA + ADP + orthophosphate => succinate + ATP + CoA-SH

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catalystActivity	[CatalystActivity:11188534] succinate-CoA ligase (ADP-forming) activity of SCS dimer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:11183465] Elser, Justin, 2025-03-26
dbId	11188536
displayName	succinyl-CoA + ADP + orthophosphate => succinate + ATP + CoA-SH
eventOf	[Pathway:R-CQI-1119533] TCA cycle (plant) - Chenopodium quinoa
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-CQI-1120286] succinate + ubiquinone => fumarate + ubiquinol - Chenopodium quinoa
inferredFrom	[Reaction:R-OSA-1121627] succinyl-CoA + ADP + orthophosphate => succinate + ATP + CoA-SH - Oryza sativa
input	[SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix] [SimpleEntity:R-ALL-70958] SUCC-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
name	succinyl-CoA + ADP + orthophosphate => succinate + ATP + CoA-SH Succinate--CoA ligase (ADP-forming)
output	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-113536] SUCCA [mitochondrial matrix]
precedingEvent	[Reaction:R-CQI-1120492] 2-oxoglutarate + coA-SH + NAD+ => succinyl-CoA + CO2 + NADH + H+ - Chenopodium quinoa
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9764178] Chenopodium quinoa
stId	R-CQI-1121627
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-CQI-1119533] TCA cycle (plant) - Chenopodium quinoa
(precedingEvent)	[Reaction:R-CQI-1120286] succinate + ubiquinone => fumarate + ubiquinol - Chenopodium quinoa
(inferredTo)	[Reaction:R-OSA-1121627] succinyl-CoA + ADP + orthophosphate => succinate + ATP + CoA-SH - Oryza sativa