Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Pathway > Entries

Activation of pre-replication complex

Go to Details

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10218449] Elser, Justin, 2025-03-24
dbId	10227246
displayName	Activation of pre-replication complex
eventOf	[Pathway:R-CCN-9640887] G1/S transition - Coffea canephora
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Pathway:R-CCN-9675824] DNA replication Initiation - Coffea canephora
hasDiagram	false
hasEvent	[Reaction:R-CCN-9645961] Association of MCM10 with pre-replication complex - Coffea canephora [Reaction:R-CCN-9645867] Recruitment of CDC45 - Coffea canephora [Reaction:R-CCN-9645934] Association of TOPBP1 with CDC45 - Coffea canephora [Reaction:R-CCN-9645845] Association of RPA proteins with Pre-RC at origin - Coffea canephora [Reaction:R-CCN-9645813] Binding of DNA polymerase alpha:primase at origin - Coffea canephora [Reaction:R-CCN-9645988] Binding of DNA polymerase epsilon at origin - Coffea canephora [Reaction:R-CCN-9645996] Displacement of CDC6 from pre-replication complex - Coffea canephora
inferredFrom	[Pathway:R-OSA-9645850] Activation of pre-replication complex - Oryza sativa
isInDisease	false
isInferred	true
name	Activation of pre-replication complex
precedingEvent	[Pathway:R-CCN-9640882] Assembly of pre-replication complex - Coffea canephora
releaseDate	2025-02-15
schemaClass	Pathway
species	[Species:9029942] Coffea canephora
stId	R-CCN-9645850
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(precedingEvent)	[Pathway:R-CCN-9675824] DNA replication Initiation - Coffea canephora
(hasEvent)	[Pathway:R-CCN-9640887] G1/S transition - Coffea canephora
(inferredTo)	[Pathway:R-OSA-9645850] Activation of pre-replication complex - Oryza sativa

© 2019 Gramene - Plant Reactome