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Synthesis of 6-10 nucelotide RNA primer at origin

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catalystActivity	[CatalystActivity:10182625] DNA-directed 5'-3' RNA polymerase activity of DNA polymerase alpha:primase:POLE:origin complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10174025] Elser, Justin, 2025-03-24
dbId	10182627
displayName	Synthesis of 6-10 nucelotide RNA primer at origin
eventOf	[Pathway:R-CCD-9675824] DNA replication Initiation - Cynara cardunculus var. scolymus
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-CCD-9675791] Synthesis of 20 nucelotide primer at origin - Cynara cardunculus var. scolymus
inferredFrom	[Reaction:R-OSA-9675867] Synthesis of 6-10 nucelotide RNA primer at origin - Oryza sativa
input	[Complex:R-CCD-9645817] DNA polymerase alpha:primase:POLE:origin complex [nucleoplasm] [DefinedSet:R-ALL-30595] NTP [nucleoplasm]
isInDisease	false
isInferred	true
name	Synthesis of 6-10 nucelotide RNA primer at origin
output	[Complex:R-CCD-9646046] POLE [nucleoplasm] [Complex:R-CCD-9675881] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm]
precedingEvent	[Reaction:R-CCD-9645813] Binding of DNA polymerase alpha:primase at origin - Cynara cardunculus var. scolymus
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9659240] Cynara cardunculus var. scolymus
stId	R-CCD-9675867
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-CCD-9675824] DNA replication Initiation - Cynara cardunculus var. scolymus
(precedingEvent)	[Reaction:R-CCD-9675791] Synthesis of 20 nucelotide primer at origin - Cynara cardunculus var. scolymus
(inferredTo)	[Reaction:R-OSA-9675867] Synthesis of 6-10 nucelotide RNA primer at origin - Oryza sativa