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Binding of DNA polymerase alpha:primase at origin

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10551356] Elser, Justin, 2025-03-25
dbId	10570849
displayName	Binding of DNA polymerase alpha:primase at origin
eventOf	[Pathway:R-BNA-9645850] Activation of pre-replication complex - Brassica napus
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-BNA-9675867] Synthesis of 6-10 nucelotide RNA primer at origin - Brassica napus
inferredFrom	[Reaction:R-OSA-9645813] Binding of DNA polymerase alpha:primase at origin - Oryza sativa
input	[Complex:R-BNA-9646026] DNA polymerase alpha:primase [nucleoplasm] [Complex:R-BNA-9645974] POLE:origin complex [nucleoplasm]
isInDisease	false
isInferred	true
name	Binding of DNA polymerase alpha:primase at origin
output	[Complex:R-BNA-9645817] DNA polymerase alpha:primase:POLE:origin complex [nucleoplasm]
precedingEvent	[Reaction:R-BNA-9645988] Binding of DNA polymerase epsilon at origin - Brassica napus [Reaction:R-BNA-9645845] Association of RPA proteins with Pre-RC at origin - Brassica napus
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9029842] Brassica napus
stId	R-BNA-9645813
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(precedingEvent)	[Reaction:R-BNA-9675867] Synthesis of 6-10 nucelotide RNA primer at origin - Brassica napus
(hasEvent)	[Pathway:R-BNA-9645850] Activation of pre-replication complex - Brassica napus
(inferredTo)	[Reaction:R-OSA-9645813] Binding of DNA polymerase alpha:primase at origin - Oryza sativa

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