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4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O

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compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10541326] Elser, Justin, 2025-03-25
dbId	10543264
displayName	4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O
eventOf	[Pathway:R-BDI-1119439] Cholesterol biosynthesis III (via desmosterol) - Brachypodium distachyon [Pathway:R-BDI-1119559] Cholesterol biosynthesis I - Brachypodium distachyon
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-BDI-1121133] 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Brachypodium distachyon
inferredFrom	[Reaction:R-OSA-1120472] 4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa
input	[SimpleEntity:R-ALL-1130992] 4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
name	4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O RXN66-310 biochemicalReaction85497
output	[SimpleEntity:R-ALL-1130831] 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9029858] Brachypodium distachyon
stId	R-BDI-1120472
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-BDI-1119439] Cholesterol biosynthesis III (via desmosterol) - Brachypodium distachyon [Pathway:R-BDI-1119559] Cholesterol biosynthesis I - Brachypodium distachyon
(precedingEvent)	[Reaction:R-BDI-1121133] 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Brachypodium distachyon
(inferredTo)	[Reaction:R-OSA-1120472] 4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa

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