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Displacement of CDC6 from pre-replication complex

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10481878] Elser, Justin, 2025-03-25
dbId	10490291
displayName	Displacement of CDC6 from pre-replication complex
eventOf	[Pathway:R-ATA-9645850] Activation of pre-replication complex - Aegilops tauschii
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-ATA-9645961] Association of MCM10 with pre-replication complex - Aegilops tauschii
inferredFrom	[Reaction:R-OSA-9645996] Displacement of CDC6 from pre-replication complex - Oryza sativa
input	[Complex:R-ATA-9640877] Pre-RC [nucleoplasm]
isInDisease	false
isInferred	true
name	Displacement of CDC6 from pre-replication complex
output	[EntityWithAccessionedSequence:R-ATA-9640886] AET3Gv20826800 [nucleoplasm] [Complex:R-ATA-9645902] Origin:ORC:MCM2-7 [nucleoplasm]
precedingEvent	[Reaction:R-ATA-9640880] Loading of MCM2-7 - Aegilops tauschii
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9029789] Aegilops tauschii
stId	R-ATA-9645996
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-ATA-9645850] Activation of pre-replication complex - Aegilops tauschii
(precedingEvent)	[Reaction:R-ATA-9645961] Association of MCM10 with pre-replication complex - Aegilops tauschii
(inferredTo)	[Reaction:R-OSA-9645996] Displacement of CDC6 from pre-replication complex - Oryza sativa

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