UniProt:Q10L71 VLN2

chain
  • chain:1-966
checksum 8EC0D8CA76E0C6B6
comment
  • FUNCTION Ca(2+)-regulated actin-binding protein (By similarity). Binds actin microfilaments (MFs). Involved in actin filament bundling, severing and capping. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. May regulate cell expansion in developing organs. Required for the regulation of plant architecture via the modulation of polar auxin transport and root gravitropism (PubMed:26486445).SUBCELLULAR LOCATION Mostly expressed in growing tissues.DISRUPTION PHENOTYPE Malformed organs, including twisted roots and shoots at the seedling stage, mainly caused by asymmetrical expansion of cells on the opposite sides of an organ. Increased dynamic actin cytoskeleton network. Hypersensitive gravitropic response, faster recycling of PIN2, and altered auxin distribution.SIMILARITY Belongs to the villin/gelsolin family.
created [InstanceEdit:9928314] Naithani, Sushma, 2024-11-13
databaseName UniProt
dbId 9928299
description
  • recommendedName: fullName evidence="6"Villin-2
displayName UniProt:Q10L71 VLN2
geneName
  • VLN2
  • Os03g0356700
  • LOC_Os03g24220
  • OSNPB_030356700
identifier Q10L71
isSequenceChanged false
keyword
  • Actin capping
  • Actin-binding
  • Auxin signaling pathway
  • Calcium
  • Cytoplasm
  • Cytoskeleton
  • Reference proteome
  • Repeat
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • VLN2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • VLN2_ORYSJ
sequenceLength 966
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10L71