| created | [InstanceEdit:9924415] |
| dbId | 9924526 |
| displayName | ELONGATED UPPERMOST INTERNODE1 (EUI1) as a GA-deactivating e... |
| literatureReference | |
| schemaClass | Summation |
| text | ELONGATED UPPERMOST INTERNODE1 (EUI1) as a GA-deactivating enzyme. It catalyzes the 16alpha,17-epoxidation on non-13-hydroxylated gibberellins (GAs), including GA4, GA9, and GA12. No activity with GA1, GA20, GA53, or ent-kaurenoic acid. Reduces the biological activity of GAs. EUI1 is a direct target of HOX12. HOX12 physically interacts with the EUI1 promoter and upregulates the expression of EUI1 transcription. Enhanced HOX12 levels promote EUI1 expression and inhibit GA4 accumulation. In contrast, diminished HOX12 expression downregulates EUI1 activity and consequently promotes the influx of GA4 into the stem, leading to enhanced panicle exsertion. Both HOX12 knockdown and eui1 plants are morphologically normal until the increased elongation of the uppermost internode occurs at the heading stage. HOX12 and EUI1 inhibit panicle exsertion from the flag leaf sheath in rice (Gao et al., 2016). |
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