UniProt:Q75KE5 ZFP36

chain
  • chain:1-220
checksum 541EF5115A8886F7
comment
  • FUNCTION Probable transcription factor involved in abscisic acid (ABA) signaling. Required for the regulation of the cross-talk between NADPH oxidase, hydrogen peroxide and MAP kinase in ABA signaling. Regulates the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK genes MPK1, MPK4, MPK5, MPK7 and MPK14. Regulates ABA-induced hydrogen peroxide production and antioxidant defense. Required for tolerance to water stress and oxidative stress.INDUCTION Induced by abscisic acid (ABA) and hydrogen peroxide.MISCELLANEOUS Plants over-expressing ZFP36 display enhanced tolerance to drought and oxidative stresses (PubMed:25071223). A natural allele in the promoter of ZFP36 in the durably resistant rice variety Digu confers broad-spectrum resistance to rice blast (Magnaporthe oryzae) (PubMed:28666113).
created [InstanceEdit:9826424] Naithani, Sushma, 2023-01-28
databaseName UniProt
dbId 9826415
description
  • recommendedName: fullName evidence="5"Zinc finger protein 36 alternativeName: fullName evidence="6"Protein BROAD-SPECTRUM RESISTANCE DIGU 1
displayName UniProt:Q75KE5 ZFP36
geneName
  • ZFP36
  • Os03g0437200
  • LOC_Os03g32230
  • BSR-D1
  • OsJ_11395
  • OSJNBa0054H04.4
  • OSJNBb0034P05.8
identifier Q75KE5
isSequenceChanged false
keyword
  • DNA-binding
  • Metal-binding
  • Reference proteome
  • Repeat
  • Stress response
  • Transcription
  • Transcription regulation
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ZFP36
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ZFP36_ORYSJ
  • A3AJF7
  • Q7X9P9
sequenceLength 220
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q75KE5