UniProt:X5HYT8 SMOS1

chain
  • chain:1-425
checksum 87036D2AE80BB325
comment
  • FUNCTION Transcription activator involved in the control of organ size (PubMed:24486766). Acts as an auxin-dependent regulator for cell expansion during organ size control (PubMed:24486766). Binds to the promoter of PHI-1, a gene that regulates cell expansion, and positively regulates its expression (PubMed:24486766). Cooperatively functions in a transactivating complex with DLT to enhance the transcription of the SMOS1 target PHI-1, and to regulate plant organ size (PubMed:28069545). Interaction between SMOS1 and DLT is a crosstalk point for auxin and brassinosteroid (BR) signaling (PubMed:28069545). Acts as a positive regulator of BR signaling (PubMed:28100707). Cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes (PubMed:28100707).SUBUNIT Interacts (via C-terminus) with DLT (PubMed:28069545). Interacts with NSP2 and SHR1 (PubMed:28069545). Interacts with BZR1 and GSK2 (PubMed:28100707).SUBCELLULAR LOCATION Localizes mostly in the nucleus.TISSUE SPECIFICITY Expressed in the apical region of leaf blades, young leaf sheaths, a broad area below the shoot apical mersistem (SAM) and near the tip of primordial leaves (PubMed:24486766). In developing roots, expressed at the tip of seminal roots and lateral root tips (PubMed:24486766). Expressed in developing nodes and basal region of internodes (PubMed:24486766). In flowers, expressed in lemma, palea and anthers (PubMed:24486766).INDUCTION Induced by auxin (PubMed:24486766). Induced by brassinosteroid (at protein level), but repressed by brassinosteroid at mRNA level probably via a negative regulatory feedback loop (PubMed:28100707).PTM Phosphorylated by GSK2 (PubMed:28100707). Phosphorylation of SMOS1 leads to its degradation by an unknown mechanism (PubMed:28100707).DISRUPTION PHENOTYPE Reduced size of various organs due to decreased cell size, increased cell number, and abnormal cell arrangement and microtubule orientation (PubMed:24486766). Brassinosteroid (BR) loss-of-function phenotype with semidwarf plants, reduced length of internodes, erect leaves, up-regulation of BR biosynthetic genes and decreased sensitivity to BR (PubMed:28100707).SIMILARITY Belongs to the AP2/ERF transcription factor family. AP2 subfamily.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:9675413] Gupta, Parul, 2020-02-04
databaseName UniProt
dbId 9675523
description
  • recommendedName: fullName evidence="8"AP2-like ethylene-responsive transcription factor SMOS1 alternativeName: fullName evidence="7"Protein REDUCED LEAF ANGLE 1 alternativeName: fullName evidence="6"Protein SMALL ORGAN SIZE 1
displayName UniProt:X5HYT8 SMOS1
geneName
  • SMOS1
  • RLA1
  • Os05g0389000
  • LOC_Os05g32270
  • OSJNBa0073E05.20
identifier X5HYT8
isSequenceChanged false
keyword
  • Activator
  • Auxin signaling pathway
  • Brassinosteroid signaling pathway
  • Cytoplasm
  • DNA-binding
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription
  • Transcription regulation
modified [InstanceEdit:9862192] Weiser, Joel, 2024-02-26
name
  • SMOS1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SMOS1_ORYSJ
  • Q0DIH8
  • Q60E56
sequenceLength 425
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/X5HYT8