UniProt:Q6ZLK0 OST48

chain
  • signal peptide:1-24
  • chain:25-439
checksum BA5F722D7DD357B7
comment
  • FUNCTION Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.PATHWAY Protein modification; protein glycosylation.SUBUNIT Component of the oligosaccharyltransferase (OST) complex.SUBCELLULAR LOCATION Belongs to the DDOST 48 kDa subunit family.
created [InstanceEdit:9675413] Gupta, Parul, 2020-02-04
databaseName UniProt
dbId 9675510
description
  • recommendedName: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit shortName: Oligosaccharyl transferase 48 kDa subunit
displayName UniProt:Q6ZLK0 OST48
geneName
  • OST48
  • Os07g0209000
  • LOC_Os07g10830
  • OJ1136_A05.21
identifier Q6ZLK0
isSequenceChanged false
keyword
  • Endoplasmic reticulum
  • Membrane
  • Reference proteome
  • Signal
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • OST48
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • OST48_ORYSJ
  • A0A0P0X412
sequenceLength 439
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6ZLK0