UniProt:Q0J290 PAO7

chain
  • signal peptide:1-27
  • chain:28-474
checksum 6D8324200D3D5F87
comment
  • FUNCTION Flavoenzyme involved in polyamine back-conversion (PubMed:24634478). Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives (PubMed:24634478). Substrate preference is spermine > spermidine > N(1)-acetylspermine > N(1)-acetylspermidine > norspermine > thermospermine (PubMed:24634478). No activity detected when putrescine is used as substrate (PubMed:24634478). May play a role in producing hydrogen peroxide for secondary wall thickening through lignin formation during anther development (Probable).CATALYTIC ACTIVITY spermine + O2 + H2O = 3-aminopropanal + spermidine + H2O2CATALYTIC ACTIVITY N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2CATALYTIC ACTIVITY norspermine + O2 + H2O = norspermidine + 3-aminopropanal + H2O2CATALYTIC ACTIVITY spermidine + O2 + H2O = 3-aminopropanal + putrescine + H2O2CATALYTIC ACTIVITY N(1)-acetylspermidine + O2 + H2O = 3-acetamidopropanal + putrescine + H2O2CATALYTIC ACTIVITY thermospermine + O2 + H2O = 3-aminopropanal + spermidine + H2O2COFACTOR Binds 1 FAD per subunit.BIOPHYSICOCHEMICAL PROPERTIES Optimum pH is 7.0 with spermidine as substrate (PubMed:24634478). Optimum pH is 6.5 with spermine as substrate (PubMed:24634478).PATHWAY Amine and polyamine degradation; spermidine degradation.PATHWAY Amine and polyamine degradation; spermine degradation.SUBCELLULAR LOCATION Specifically expressed during anther development, from the meiosis/tetrad pollen stage to the tricellular pollen stage, with a peak at the bicellular pollen stage.SIMILARITY Belongs to the flavin monoamine oxidase family.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:9658642] Gupta, Parul, 2019-08-16
databaseName UniProt
dbId 9658671
description
  • recommendedName: fullName evidence="5"Polyamine oxidase 7 shortName evidence="5"OsPAO7 ecNumber evidence="4"1.5.3.-
displayName UniProt:Q0J290 PAO7
geneName
  • PAO7
  • Os09g0368500
  • LOC_Os09g20284
  • OSNPB_090368500
identifier Q0J290
isSequenceChanged false
keyword
  • Apoplast
  • FAD
  • Flavoprotein
  • Glycoprotein
  • Oxidoreductase
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • PAO7
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PAO7_ORYSJ
  • Q6H5M6
sequenceLength 474
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0J290