UniProt:Q2QMN7 UAH

chain
  • signal peptide:1-28
  • chain:29-484
checksum 4BC65DC32DF37591
comment
  • FUNCTION Involved in the catabolism of purine nucleotides. The sequential activity of AAH, UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea.CATALYTIC ACTIVITY (S)-ureidoglycolate + H2O + 2 H(+) = glyoxylate + 2 NH4(+) + CO2COFACTOR Binds 2 manganese ions per subunit.BIOPHYSICOCHEMICAL PROPERTIES Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1.SUBUNIT Homodimer.SUBCELLULAR LOCATION Belongs to the peptidase M20 family.
created [InstanceEdit:9658580] Gupta, Parul, 2019-08-16
databaseName UniProt
dbId 9658578
description
  • recommendedName: fullName evidence="5"Ureidoglycolate hydrolase shortName evidence="5"OsUAH ecNumber evidence="4"3.5.1.116
displayName UniProt:Q2QMN7 UAH
geneName
  • UAH
  • Os12g0597500
  • LOC_Os12g40550
  • OsJ_36749
identifier Q2QMN7
isSequenceChanged false
keyword
  • Endoplasmic reticulum
  • Hydrolase
  • Manganese
  • Metal-binding
  • Purine metabolism
  • Reference proteome
  • Signal
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • UAH
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • UAH_ORYSJ
  • A0A0P0YC33
  • B9GE33
  • Q0IM51
sequenceLength 484
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q2QMN7