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[InstanceEdit:9640855] Gupta, Parul, 2019-04-03
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9640872
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In G1/S phase, formation of pre-replication complex (Pre-RC)...
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[InstanceEdit:9646027] Gupta, Parul, 2019-05-17
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Summation
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In G1/S phase, formation of pre-replication complex (Pre-RC) takes place. The first step of the pre-RC assembly is the binding of ORCs to DNA. In presence of ATP (non-hydrolysable) ORCs bind tightly with chromosomal replication origins followed by recruitment of Cdc6, CDT1 and the MCM2-7 heterohexamer onto dsDNA.
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