UniProt:Q10CI8 ORC5

chain
  • chain:1-524
checksum 6CE37D71C4326B4C
comment
  • FUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.SUBCELLULAR LOCATION Expressed at low levels in the shoot apical meristem (SAM), leaves, ears and roots.INDUCTION Reduced expression upon sucrose depletion-mediated cell proliferation arrest, and accumulates after sucrose treatment.SIMILARITY Belongs to the ORC5 family.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:9640652] Gupta, Parul, 2019-04-03
databaseName UniProt
dbId 9640637
description
  • recommendedName: fullName evidence="6"Origin of replication complex subunit 1 shortName evidence="6"OsORC1
displayName UniProt:Q10CI8 ORC5
geneName
  • ORC5
  • LOC_Os03g55200
  • Os03g0759500
  • OsJ_12664
  • OSJNBb0048A17.14
identifier Q10CI8
isSequenceChanged false
keyword
  • ATP-binding
  • DNA replication
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ORC5
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ORC5_ORYSJ
  • A0A0P0W393
  • B9F5T4
  • Q852R2
  • Q94HA9
sequenceLength 524
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10CI8