UniProt:Q5N8Q4 ORC4

chain
  • chain:1-470
checksum 90F16CBB4211525F
comment
  • FUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.SUBCELLULAR LOCATION Expressed in the shoot apical meristem (SAM), leaves, ears and roots (including root tips).INDUCTION Reduced expression upon sucrose depletion-mediated cell proliferation arrest, and accumulates after sucrose treatment.SIMILARITY Belongs to the ORC4 family.
created [InstanceEdit:9640652] Gupta, Parul, 2019-04-03
databaseName UniProt
dbId 9640631
description
  • recommendedName: fullName evidence="5"Origin of replication complex subunit 4 shortName evidence="5"OsORC4
displayName UniProt:Q5N8Q4 ORC4
geneName
  • ORC4
  • LOC_Os01g49010
  • Os01g0683400
  • OsJ_03032
  • P0445E10.9
identifier Q5N8Q4
isSequenceChanged false
keyword
  • Alternative splicing
  • ATP-binding
  • DNA replication
  • DNA-binding
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ORC4
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ORC4_ORYSJ
  • A0A0P0V6N4
  • B9EYM5
  • Q7Y0X0
sequenceLength 470
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q5N8Q4