UniProt:Q2R482 MCM2

chain
  • chain:1-961
checksum B36AB1D62B8D38BB
comment
  • FUNCTION Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. Can complement the fission yeast mcm2 mutant.CATALYTIC ACTIVITY ATP + H2O = ADP + phosphate + H(+)SUBUNIT Component of the minichromosome maintenance (MCM) complex, a heterotetramer composed of MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7 (By similarity). Interacts with CSN5 (PubMed:18755073).SUBCELLULAR LOCATION Widely expressed, with higher expression in developing tissues.SIMILARITY Belongs to the MCM family.
created [InstanceEdit:9640652] Gupta, Parul, 2019-04-03
databaseName UniProt
dbId 9640623
description
  • recommendedName: fullName evidence="7"DNA replication licensing factor MCM2 ecNumber evidence="7"3.6.4.12 alternativeName: fullName evidence="6"Minichromosome maintenance protein 2 shortName evidence="6"OsMCM2
displayName UniProt:Q2R482 MCM2
geneName
  • MCM2
  • Os11g0484300
  • LOC_Os11g29380
  • OsJ_33907
identifier Q2R482
isSequenceChanged false
keyword
  • ATP-binding
  • Cell cycle
  • DNA replication
  • DNA-binding
  • Helicase
  • Hydrolase
  • Metal-binding
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • MCM2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • MCM2_ORYSJ
  • A0A0N7KSX8
sequenceLength 961
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q2R482