UniProt:Q5VRD7 CDT3

chain
  • chain:1-53
checksum 76B90CE464999625
comment
  • FUNCTION Confers resistance to heavy metal ions (e.g. aluminium) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation (PubMed:23888867). Binds to and confers tolerance to aluminium (Al) (PubMed:23888867).SUBCELLULAR LOCATION Mostly expressed in roots at low levels and, to a lower extent, in shoots (PubMed:23888867). Observed in all cell types of both root tips and mature regions (at protein level) (PubMed:23888867).INDUCTION Accumulates in roots upon aluminium (Al) exposure in an STAR3/ART1-dependent manner (at protein level) (PubMed:23888867). Up-regulated in shoot tissues in response to cadmium (CdCl(2)) (PubMed:19017626).DISRUPTION PHENOTYPE Decreased tolerance to aluminium (Al), but normal tolerance to cadmium (Cd) (PubMed:23888867). Lower Al accumulation in root cell walls and plasma membranes but increased Al levels in root cell sap of plants exposed to aluminium (PubMed:23888867).SIMILARITY Belongs to the CYSTM1 family.
created [InstanceEdit:9639079] Gupta, Parul, 2019-03-08
databaseName UniProt
dbId 9639095
description
  • recommendedName: fullName evidence="4 5"Protein CADMIUM TOLERANCE 3 shortName evidence="4 5"Cd tolerant 3 shortName evidence="4 5"OsCDT3
displayName UniProt:Q5VRD7 CDT3
geneName
  • CDT3
  • Os01g0178300
  • OsJ_00601
identifier Q5VRD7
isSequenceChanged false
keyword
  • Cell membrane
  • Membrane
  • Metal-binding
  • Reference proteome
  • Stress response
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • CDT3
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CDT3_ORYSJ
  • Q5VRU4
sequenceLength 53
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q5VRD7