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Phytic acid (myo-inositol-1,2,3,4,5,6-hexakisphosphate) is a storage form of phosphorus in plants. It accounts for over two-thirds of the total P in rice seeds and cannot be digested by humans. It can strongly bind to nutritionally important mineral cations e.g., Ca2+, Zn2+, and Fe2+, thus considered as an anti-nutrient. In lipid independent pathway, enzymes involve in the metabolism of inositol phosphates to synthesize phytic acid are 1d-myo-inositol 3-phosphate synthase (MIPS), inositol monophosphatase (IMP), 2-Phosphoglycerate kinase (2-PGK), inositol 1,4,5-tris-phosphate kinase/inositol polyphosphate kinase (IPK), inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK), and inositol 1,3,4-triskisphosphate 5/6-kinase (ITP5/6K) (Suzuki et al., 2007; Perera et al., 2018).
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