UniProt:Q10PL5 ITPK2

chain
  • chain:1-349
checksum 6759CDB676A83E67
comment
  • FUNCTION Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and participates in phytic acid biosynthesis in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds (By similarity). May be involved in the negative regulation of osmotic stress signaling (PubMed:18421420, PubMed:22038091).CATALYTIC ACTIVITY 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)CATALYTIC ACTIVITY 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)CATALYTIC ACTIVITY 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+)COFACTOR Binds 2 magnesium ions per subunit.SUBUNIT Monomer.SUBCELLULAR LOCATION Expressed in roots, leaves, flowers, anthers and embryos.INDUCTION By drought and salt stresses.DISRUPTION PHENOTYPE No visible phenotype under normal growth conditions, but mutant plants show increased sensitivity to salt and drought stresses.SIMILARITY Belongs to the ITPK1 family.
created [InstanceEdit:9639007] Gupta, Parul, 2019-03-08
databaseName UniProt
dbId 9639030
description
  • recommendedName: fullName evidence="10"Inositol-tetrakisphosphate 1-kinase 2 ecNumber evidence="10"2.7.1.134 alternativeName: fullName evidence="10"Inositol 1,3,4-trisphosphate 5/6-kinase 2 shortName evidence="10"Inositol-triphosphate 5/6-kinase 2 shortName evidence="10"Ins(1,3,4)P(3) 5/6-kinase 2 shortName evidence="7"OsITP5/6K-2 shortName evidence="9"OsITPK2 ecNumber evidence="10"2.7.1.159 alternativeName: fullName evidence="8"OsITL1 alternativeName: fullName evidence="9"Protein DROUGHT- AND SALT-SENSITIVE MUTANT 3 shortName evidence="9"OsDSM3
displayName UniProt:Q10PL5 ITPK2
geneName
  • ITPK2
  • DSM3
  • ITL1
  • Os03g0230500
  • LOC_Os03g12840
  • OJ1017C11.3
  • OJ1781E12.6
  • OsJ_10020
identifier Q10PL5
isSequenceChanged false
keyword
  • ATP-binding
  • Endoplasmic reticulum
  • Kinase
  • Magnesium
  • Metal-binding
  • Nucleotide-binding
  • Reference proteome
  • Transferase
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ITPK2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ITPK2_ORYSJ
  • A0A0P0VUY1
  • A1KXK8
  • B9F6M0
  • Q8GSI5
sequenceLength 349
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10PL5