UniProt:P46609 OSH1

chain
  • chain:1-361
checksum 2DDC03667D7716B3
comment
  • FUNCTION Transcription factor that regulates genes involved in development. May be involved in shoot formation during embryogenesis. Overexpression in transgenic plants causes altered leaf morphology (PubMed:10488233, PubMed:8755613, PubMed:9869405). Regulates anther dehiscence via direct repression of the auxin biosynthetic gene YUCCA4 (PubMed:29915329). Binds to the DNA sequence 5'-TGAC-3' in the promoter of the YUCCA4 gene and represses its activity during anther development (PubMed:29915329). Reduction of auxin levels at late stage of anther development, after meiosis of microspore mother cells, is necessary for normal anther dehiscence and seed setting (PubMed:29915329).SUBUNIT Interacts with FTIP7.SUBCELLULAR LOCATION Localizes mainly in the nucleus (PubMed:29915329). Translocation from the cytoplasm to the nucleus is facilitated by FTIP7 (PubMed:29915329).ALTERNATIVE PRODUCTS Expressed predominantly in shoot apices. Also found to a lesser extent in glumes.DEVELOPMENTAL STAGE Expressed in the globular stage embryo 2 days after pollination (DAP) in a restricted small region just below the center of the ventral region of the embryo, where the shoot apex arises later. From 3 to 4 DAP expressed in an enlarged ventral region of embryo, corresponding to the expected epiblast and radicle, respectively. At the shoot apex differentiation stage (4-5 DAP), expressed in the shoot apex, epiblast, radicle primordia, and in their intervening tissues. Expression in the radicle is observed in the cells surrounding the root apical meristem in a donut shape but not in the meristem. During the first and second leaf primordium formation, expression pattern is maintained, but decreases. During inflorescence development, expressed only in the corpus of the rachis primordium but not in the tunica layer (L1). After floral induction, expressed in both tunica and corpus but not in floral organ primordia. Later in flower development, expressed in the corpus of the floral meristem.DISRUPTION PHENOTYPE Early termination of shoot meristems, reduced leaf formation and reduced seed setting.SIMILARITY Belongs to the TALE/KNOX homeobox family.
created [InstanceEdit:9631599] Gupta, Parul, 2018-12-10
databaseName UniProt
dbId 9631642
description
  • recommendedName: Homeobox protein knotted-1-like 6 alternativeName: Homeobox protein OSH1 alternativeName: Homeobox protein knotted-1-like 1 shortName: Oskn1
displayName UniProt:P46609 OSH1
geneName
  • OSH1
  • Os03g0727000
  • LOC_Os03g51690
  • OSJNBa0013A09.5
identifier P46609
isSequenceChanged false
keyword
  • Alternative splicing
  • Cytoplasm
  • DNA-binding
  • Homeobox
  • Nucleus
  • Reference proteome
  • Repressor
  • Transcription
  • Transcription regulation
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • OSH1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KNOS6_ORYSJ
  • Q0DNY5
  • Q10DL4
  • Q10DL5
  • Q75GJ3
sequenceLength 361
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/P46609