UniProt:Q8S0S6 GA2OX3

chain
  • chain:1-327
checksum 650793027ACA6FCE
comment
  • FUNCTION Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development (PubMed:12736788, PubMed:18952778). In vitro, converts GA1, GA20, and GA29 to the corresponding 2-beta-hydroxylated products GA8, GA29-catabolite, respectively (PubMed:12736788).CATALYTIC ACTIVITY gibberellin A1 + 2-oxoglutarate + O2 = gibberellin A8 + succinate + CO2COFACTOR Binds 1 Fe(2+) ion per subunit.TISSUE SPECIFICITY Expressed in roots, shoot apex, leaf blades, leaf sheaths, stems and flowers.INDUCTION Induced by gibberellin.MISCELLANEOUS Plants overexpressing GA2OX3 exhibit extremely dwarf phenotype and are unable to achieve phase transition from vegetative to reproductive growth.SIMILARITY Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
created [InstanceEdit:9631599] Gupta, Parul, 2018-12-10
databaseName UniProt
dbId 9631638
description
  • recommendedName: fullName evidence="6"Gibberellin 2-beta-dioxygenase 3 ecNumber evidence="3"1.14.11.13 alternativeName: fullName evidence="6"Gibberellin 2-beta-hydroxylase 3 alternativeName: fullName evidence="5"Gibberellin 2-oxidase 3 shortName evidence="5"GA 2-oxidase 3 shortName evidence="5"OsGA2ox3
displayName UniProt:Q8S0S6 GA2OX3
geneName
  • GA2OX3
  • Os01g0757200
  • LOC_Os01g55240
  • OJ1414_E05.17
identifier Q8S0S6
isSequenceChanged false
keyword
  • 3D-structure
  • Dioxygenase
  • Iron
  • Metal-binding
  • Oxidoreductase
  • Reference proteome
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • GA2OX3
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • G2OX3_ORYSJ
sequenceLength 327
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q8S0S6