UniProt:Q10NQ3 Os03g0262900

chain
  • chain:1-480
checksum 85CDD2E9FF1D1527
comment
  • FUNCTION Functions as a guanine nucleotide exchange factor (GEF) for Rab small GTPases. Activates specifically RAB5A protein (Probable). Functions cooperatively with RAB5A to regulate post-Golgi dense vesicle-mediated transport of storage proteins to the type II protein bodies (PBII) protein storage vacuoles in developing endosperm (PubMed:23723154).SUBUNIT Interacts with RAB5A (PubMed:23723154, PubMed:24488962). Interacts with GPA3 (via C-terminus) (PubMed:24488962).SUBCELLULAR LOCATION Expressed in trans-Golgi network and prevacuolar compartment when recruited by GPA3.DISRUPTION PHENOTYPE Accumulation of proglutelins in seed endosperm (PubMed:23723154). Abnormal organization of the protein storage vesicles (type II protein bodies), and formation of secretory vesicle-like structures (paramural bodies) charged with dense vesicles in seed endosperm (PubMed:23723154).
created [InstanceEdit:9626508] Gupta, Parul, 2018-10-27
databaseName UniProt
dbId 9626439
description
  • recommendedName: fullName evidence="6"Vacuolar protein sorting-associated protein 9A shortName evidence="6"OsVPS9A alternativeName: fullName evidence="6"Protein GLUTELIN PRECURSOR ACCUMULATION 2
displayName UniProt:Q10NQ3 Os03g0262900
geneName
  • Os03g0262900
  • LOC_Os03g15650
  • VPS9A
  • GPA2
  • OsJ_10226
identifier Q10NQ3
isSequenceChanged false
keyword
  • Cytoplasm
  • Golgi apparatus
  • GTP-binding
  • GTPase activation
  • Nucleotide-binding
  • Protein transport
  • Reference proteome
  • Transport
modified [InstanceEdit:9862192] Weiser, Joel, 2024-02-26
name
  • VPS9A
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • VPS9A_ORYSJ
  • Q0DT93
sequenceLength 480
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q10NQ3