UniProt:Q6ZFZ4 Os02g0709400

chain
  • signal peptide:1-33
  • chain:34-2162
  • propeptide:34-
checksum 9FF44A8AE2B23F0B
comment
  • FUNCTION Essential protease involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active.SUBCELLULAR LOCATION Ubiquitously expressed with higher levels in embryos, vasculatures, leaf primordia, leaf margins, and shoot apical meristem (SAM).DOMAIN The transmembrane regions are not required for calpain activity but may play regulatory roles.PTM Autocatalytic proteolytic cleavage leading to the production of mainly cytoplasmic localized subproducts of about 85 and 120 kDa.DISRUPTION PHENOTYPE Abnormal embryos arrested at the globular stage with an abnormal aleurone layer on the ventral side.MISCELLANEOUS Although homology to other calpains is high within the protease domain, the lack of calcium-binding sites suggests that this protein is a protease that may not be activated by calcium ions.SIMILARITY Belongs to the peptidase C2 family.
created [InstanceEdit:9623489] Gupta, Parul, 2018-10-04
databaseName UniProt
dbId 9623483
description
  • recommendedName: Calpain-type cysteine protease ADL1 ecNumber: 3.4.22.- alternativeName: Phytocalpain ADL1 alternativeName: Protein ADAXIALIZED LEAF1 alternativeName: Protein DEFECTIVE KERNEL 1 shortName: OsDEK1 alternativeName: Protein SHOOTLESS 3
displayName UniProt:Q6ZFZ4 Os02g0709400
geneName
  • Os02g0709400
  • LOC_Os02g47970
  • ADL1
  • DEK1
  • ODM63
  • SHL3
  • OJ1311_H06.4
identifier Q6ZFZ4
isSequenceChanged false
keyword
  • Cell membrane
  • Cytoplasm
  • Developmental protein
  • Endoplasmic reticulum
  • Endosome
  • Hydrolase
  • Membrane
  • Phosphoprotein
  • Protease
  • Reference proteome
  • Repeat
  • Signal
  • Thiol protease
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • ADL1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • DEK1_ORYSJ
  • Q8RYA5
sequenceLength 2162
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6ZFZ4