UniProt:B9F4Q9 Os02g0244100

chain
  • chain:1-425
checksum 9FB16AB6E21EF09C
comment
  • FUNCTION E3 ubiquitin-protein ligase involved in the regulation of grain size. May limit grain width and weight by restricting cell proliferation of the spikelet hull. Possesses E3 ubiquitin-protein ligase activity in vitro.CATALYTIC ACTIVITY S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.PATHWAY Protein modification; protein ubiquitination.SUBCELLULAR LOCATION Expressed in roots, shoots, leaves, inflorescence meristems, stamens, pistils, spikelet hulls and endosperms 4 days after fertilization.MISCELLANEOUS Plants silencing GW2 produce grains with increased width, resulting in enhanced grain weight, whereas overexpression of GW2 decreases grain size and weight. The naturally occurring WY3 allele of GW2, which encodes a truncated version of the protein with a 310-amino acid deletion, increases the number of cells of the spikelet hull, resulting in a wider spikelet hull, and subsequently accelerates the grain milk filling rate, resulting in increased grain width, weight and yield.
created [InstanceEdit:9622314] Gupta, Parul, 2018-09-28
databaseName UniProt
dbId 9622207
description
  • recommendedName: fullName evidence="4"E3 ubiquitin-protein ligase GW2 ecNumber evidence="2"2.3.2.27 alternativeName: fullName evidence="3"Protein GRAIN WIDTH AND WEIGHT 2 alternativeName: fullName evidence="4"RING-type E3 ubiquitin transferase GW2
displayName UniProt:B9F4Q9 Os02g0244100
geneName
  • Os02g0244100
  • LOC_Os02g14720
  • GW2
  • OsJ_06048
  • P0503B05.32
identifier B9F4Q9
isSequenceChanged false
keyword
  • Cytoplasm
  • Developmental protein
  • Metal-binding
  • Reference proteome
  • Transferase
  • Ubl conjugation pathway
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • GW2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • GW2_ORYSJ
  • Q6ESV2
sequenceLength 425
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/B9F4Q9