UniProt:A0A0P0XII1 Os08g0538300

chain
  • signal peptide:1-18
  • chain:19-624
checksum 62635BB84B57C9CE
comment
  • FUNCTION Lysin motif (LysM) receptor kinase required as a cell surface receptor for chitin elicitor (chitooligosaccharides) signaling leading to innate immunity in response to biotic stresses. Involved in the resistance to pathogenic fungi, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patterns (PAMP) (PubMed:21070404, PubMed:22891159, PubMed:24964058). Involved in the detection of microbial peptidoglycans (PGNs) and mediates PGN response (PubMed:24964058). Plays dual roles in PGN and chitin signaling during innate immunity. Acts as an adapter for LYP4 and LYP6 and mediates signal transduction from the extracellular to intracellular spaces. Participates in the activation of defense genes during response to PGN and chitin (PubMed:25335639). Phosphorylates the downstream partner RLCK185 in response to chitin elicitation (PubMed:23498959).CATALYTIC ACTIVITY L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)CATALYTIC ACTIVITY L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)SUBUNIT Homooligomer. Interacts with CEBIP (PubMed:21070404). Interacts with LYP4 and LYP6 (PubMed:24964058, PubMed:25335639). Interacts with RLCK176 (PubMed:25335639).SUBCELLULAR LOCATION Expressed in seedlings, roots, shoots and stems, and, to a lower extent, in flowers.PTM Autophosphorylated; induced by chitin and derivatives.DISRUPTION PHENOTYPE Suppression of the defense responses induced by chitin oligosaccharides.SIMILARITY Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:9611567] Naithani, Sushma, 2018-06-18
databaseName UniProt
dbId 9611420
description
  • recommendedName: fullName evidence="12"Chitin elicitor receptor kinase 1 shortName evidence="12"OsCERK1 ecNumber evidence="9"2.7.11.1 alternativeName: fullName evidence="13"LysM domain receptor-like kinase 1 shortName evidence="13"LysM RLK1 shortName evidence="13"LysM-containing receptor-like kinase 1 alternativeName: fullName evidence="12"LysM domain receptor-like kinase 9 shortName evidence="12"OsLysM-RLK9
displayName UniProt:A0A0P0XII1 Os08g0538300
geneName
  • Os08g0538300
  • CERK1
  • RLK9
  • LOC_Os08g42580
  • P0665C04.34
  • P0666G10.101
identifier A0A0P0XII1
isSequenceChanged false
keyword
  • 3D-structure
  • ATP-binding
  • Cell membrane
  • Chitin-binding
  • Disulfide bond
  • Glycoprotein
  • Immunity
  • Innate immunity
  • Kinase
  • Membrane
  • Nucleotide-binding
  • Plant defense
  • Receptor
  • Reference proteome
  • Serine/threonine-protein kinase
  • Signal
  • Transferase
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • CERK1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CERK1_ORYSJ
  • B7F461
  • Q0J431
  • Q6ZD33
sequenceLength 624
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/A0A0P0XII1