UniProt:A4KAG8 Os02g0571800

chain
  • chain:1-821
checksum 2191522B9B719A5D
comment
  • FUNCTION Involved in the biosynthesis of ent-kaurene diterpenoids natural products (PubMed:16861806, PubMed:17456599). Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-isokaur-15-ene (PubMed:16861806, PubMed:17456599).CATALYTIC ACTIVITY ent-copalyl diphosphate = ent-isokaurene + diphosphateCOFACTOR Binds 3 Mg(2+) ions per subunit.PATHWAY Secondary metabolite biosynthesis; terpenoid biosynthesis.TISSUE SPECIFICITY Expressed in roots and stems.DOMAIN The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).MISCELLANEOUS Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation).SIMILARITY Belongs to the terpene synthase family.
created [InstanceEdit:9610732] Gupta, Parul, 2018-06-11
databaseName UniProt
dbId 9610727
description
  • recommendedName: fullName evidence="8"Ent-isokaur-15-ene synthase ecNumber evidence="4 5"4.2.3.103 alternativeName: fullName evidence="6"Ent-kaurene synthase-like 5 shortName evidence="6"OsKS5 alternativeName: fullName evidence="7"Ent-kaurene synthase-like 6 shortName evidence="7"OsKS6 shortName evidence="7"OsKSL6 alternativeName: fullName evidence="8"Iso-kaurene synthase
displayName UniProt:A4KAG8 Os02g0571800
geneName
  • Os02g0571800
  • LOC_Os02g36264
  • KSL6
  • KS5
  • P0689H05.34
identifier A4KAG8
isSequenceChanged false
keyword
  • Lyase
  • Magnesium
  • Metal-binding
  • Plant defense
  • Reference proteome
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • KSL6
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KSL6_ORYSJ
  • A0A0P0VKP2
  • Q0E083
  • Q2PHF1
  • Q69DS6
  • Q6Z5J0
sequenceLength 821
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/A4KAG8