OsPHO2, an ubiquitin-conjugating enzyme, plays key role in u...

created [InstanceEdit:9031336] Gupta, Parul, 2017-11-29
dbId 9031142
displayName OsPHO2, an ubiquitin-conjugating enzyme, plays key role in u...
schemaClass Summation
text OsPHO2, an ubiquitin-conjugating enzyme, plays key role in ubiquitin-mediated protein degradation pathway. OsPHO2 functions as a negative regulator that can repress its target gene expression by protein degradation. It regulates Pi translocation and remobilization by regulating the expression of Pht1 transporters. OsPHO2 is an important component of phosphate signaling pathway and negatively regulated by OsmiR399. Mutation of OsPHO2 causes over-accumulation of Pi in blades and disrupts Pi remobilization between tissues and organs under Pi-sufficient conditions. OsPHO2 regulates the activity of acid phosphatases and ribonucleases through activating the expression of related genes in rice roots.