UniProt:Q75HA6 NPR3

chain
  • chain:1-589
checksum 4B3F1F541F1CC56F
comment
  • FUNCTION Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in defense response against the bacterial blight disease caused by Xanthomonas oryzae pv. oryzae (Xoo). Plants expressing an NPR3/NH3 transgene driven by its native promoter show enhanced resistance to the Xoo pathogen, and exhibit elevated sensitivity to benzothiadiazole (BTH) treatment and enhanced induction of defense-related genes upon treatment with BTH (PubMed:20561248). Intriguingly, constitutive over-expression of NPR3/NH3 with a ubiquitin promoter does not confer disease resistance to Xoo (PubMed:17309686).PATHWAY Protein modification; protein ubiquitination.SUBUNIT Interacts with TGA2.1, TGA2.2, TGA2.3, LG2, TGAL1, TGAL4, NRR, RH1, RH2 and RH3.SUBCELLULAR LOCATION The BTB/POZ domain mediates the interaction with some component of ubiquitin ligase complexes.SIMILARITY Belongs to the plant 'ANKYRIN-BTB/POZ' family. 'NPR1-like' subfamily.
created [InstanceEdit:6787965] Amarasinghe, Vindhya, 2015-07-18
databaseName UniProt
dbId 6787939
description
  • recommendedName: fullName evidence="12"BTB/POZ domain and ankyrin repeat-containing protein NPR3 shortName evidence="10"OsNPR3
displayName UniProt:Q75HA6 NPR3
geneName
  • NPR3
  • NH3
  • Os03g0667100
  • LOC_Os03g46440
  • OsJ_12014
  • OSJNBa0056E06.6
identifier Q75HA6
isSequenceChanged false
keyword
  • Alternative splicing
  • ANK repeat
  • Metal-binding
  • Nucleus
  • Plant defense
  • Reference proteome
  • Repeat
  • Ubl conjugation pathway
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9917590] Weiser, Joel, 2024-08-09
name
  • NPR3
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • NPR3_ORYSJ
  • Q75HA7
  • Q75HA8
sequenceLength 589
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q75HA6