UniProt:Q6K209 CAL1

chain
  • signal peptide:1-31
  • chain:32-80
checksum 3326C0461F10A1CA
comment
  • FUNCTION Plant defensin-like protein involved in accumulation of cadmium (Cd) in rice leaves. Mediates Cd efflux from cytosol into extracellular spaces via chelation. This drives Cd secretion from xylem parenchyma cells into the xylem vessels, hence lowering Cd levels in cytosol meanwhile promoting Cd translocation from roots to shoots.SUBCELLULAR LOCATION Expressed preferentially in root exodermis and xylem parenchyma cells in vasculature of root and flag leaf sheath.INDUCTION Induced by cadmium in roots (PubMed:29440679). Down-regulated by cold stress (PubMed:19279197).BIOTECHNOLOGY Rice varieties with high CAL1 activity over-accumulate cadmium (Cd) in rice straws, but are not affected by Cd accumulation, or the accumulation of other essential metals in rice grains. These functional characteristics could be used to breed dual-function rice varieties that produce safe grains while remediating paddy soils.SIMILARITY Belongs to the DEFL family.
created [InstanceEdit:6787061] Amarasinghe, Vindhya, 2015-07-10
databaseName UniProt
dbId 6787206
description
  • recommendedName: fullName evidence="7"Defensin-like protein CAL1 alternativeName: fullName evidence="5"OsCPT1 alternativeName: fullName evidence="7"Pathogen-related protein 12 shortName evidence="7"OsPR12 alternativeName: fullName evidence="6"Protein CADMIUM ACCUMULATION IN LEAF 1
displayName UniProt:Q6K209 CAL1
geneName
  • CAL1
  • CPT1
  • PR12
  • Os02g0629800
  • LOC_Os02g41904
  • B1469H02.30
  • OsJ_07607
identifier Q6K209
isSequenceChanged false
keyword
  • 3D-structure
  • Cadmium
  • Disulfide bond
  • Metal-binding
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
name
  • CAL1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • CAL1_ORYSJ
sequenceLength 80
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6K209