UniProt:Q6YV04 HDAC2

chain
  • chain:1-509
checksum E3F48D23EE3A2C41
comment
  • FUNCTION Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.CATALYTIC ACTIVITY N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetateCOFACTOR Binds 1 zinc ion per subunit.SUBCELLULAR LOCATION Expressed in roots.INDUCTION Induced by drought and salt stresses.MISCELLANEOUS Plants silencing HDAC3 exhibit semi-dwarf phenotype.SIMILARITY Belongs to the histone deacetylase family. HD Type 1 subfamily.
created [InstanceEdit:6787061] Amarasinghe, Vindhya, 2015-07-10
databaseName UniProt
dbId 6787081
description
  • recommendedName: fullName evidence="6"Histone deacetylase 2 shortName evidence="6"OsHDAC2 ecNumber evidence="1"3.5.1.98
displayName UniProt:Q6YV04 HDAC2
geneName
  • HDAC2
  • HDA710
  • Os02g0215200
  • LOC_Os02g12380
  • B1307A11.3-1
  • OJ1006_D05.31-1
  • OsJ_05884
identifier Q6YV04
isSequenceChanged false
keyword
  • Alternative splicing
  • Chromatin regulator
  • Hydrolase
  • Metal-binding
  • Nucleus
  • Reference proteome
  • Repressor
  • Transcription
  • Transcription regulation
  • Zinc
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • HDAC2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • HDAC2_ORYSJ
  • B9F497
  • Q0E2T7
  • Q7Y0Y7
sequenceLength 509
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q6YV04