UniProt:Q7Y0Y6 Os02g0214900

chain
  • chain:1-510
checksum 664090CF78C12535
comment
  • FUNCTION Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.CATALYTIC ACTIVITY N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetateCOFACTOR Binds 1 zinc ion per subunit.SUBCELLULAR LOCATION Expressed in roots.INDUCTION Induced by drought and salt stresses.MISCELLANEOUS Plants silencing HDAC3 exhibit reduced peduncle elongation and fertility.SIMILARITY Belongs to the histone deacetylase family. HD Type 1 subfamily.
created [InstanceEdit:6787061] Amarasinghe, Vindhya, 2015-07-10
databaseName UniProt
dbId 6786940
description
  • recommendedName: fullName evidence="6"Histone deacetylase 3 shortName evidence="6"OsHDAC3 ecNumber evidence="1"3.5.1.98
displayName UniProt:Q7Y0Y6 Os02g0214900
geneName
  • Os02g0214900
  • OJ1006_D05.27-1
  • HDAC3
  • HDA703
  • LOC_Os02g12350
identifier Q7Y0Y6
isSequenceChanged false
keyword
  • Chromatin regulator
  • Hydrolase
  • Metal-binding
  • Nucleus
  • Reference proteome
  • Repressor
  • Transcription
  • Transcription regulation
  • Zinc
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • HDAC3
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • HDAC3_ORYSJ
sequenceLength 510
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q7Y0Y6