UniProt:Q5Z807 LIC

chain
  • chain:1-390
checksum 806E8A1CD2B35F7D
comment
  • FUNCTION Transcriptional activator that binds double-stranded DNA and the single-stranded RNA polymers poly(rA), poly(rU) and poly(rG), but not poly(rC). Mediates optimal plant architecture through brassinosteroid (BR) signaling. May act as a negative regulator in sterol homeostasis (PubMed:18953406). Acts as a negative regulator of BR signaling. Binds to the specific DNA sequence 5'-CTCGC-3' of BZR1 promoter and negatively regulates BZR1. Acts as an antagonistic transcription factor of BZR1 to attenuate the BR signaling pathway and regulate leaf bending. Represses the expression of ILI1, and activates that of IBH1 to balance the regulation activity of BZR1 (PubMed:22570626).SUBUNIT Interacts with GSK1 and GSK4.SUBCELLULAR LOCATION Brassinosteroid promotes nuclear localization. Phosphorylation represses nuclear localization.TISSUE SPECIFICITY Expressed in the adaxial face of the collar, nodes and the basal region of elongating internodes.INDUCTION Induced by 24-epibrassinolide.PTM Phosphorylated on serine and threonine residues by GSK1. Phosphorylation represses nuclear localization.MISCELLANEOUS Plants silencing LIC are short, have increased leaf and tiller angles, and display both reduced number of rachises and seeds (PubMed:18953406). Plants over-expressing LIC show erect leaves (PubMed:22570626).
created [InstanceEdit:5632076] Amarasinghe, Vindhya, 2014-10-28
databaseName UniProt
dbId 5632042
description
  • recommendedName: Zinc finger CCCH domain-containing protein 46 shortName: OsC3H46 alternativeName: fullName evidence="5"Protein LEAF AND TILLER ANGLE INCREASED CONTROLLER shortName evidence="5"OsLIC
displayName UniProt:Q5Z807 LIC
geneName
  • LIC
  • Os06g0704300
  • LOC_Os06g49080
  • OJ1215_E11.23
identifier Q5Z807
isSequenceChanged false
keyword
  • Activator
  • Brassinosteroid signaling pathway
  • Cytoplasm
  • DNA-binding
  • Metal-binding
  • Nucleus
  • Reference proteome
  • Transcription
  • Transcription regulation
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9862192] Weiser, Joel, 2024-02-26
name
  • LIC
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • C3H46_ORYSJ
  • A0A0P0X0K1
sequenceLength 390
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q5Z807