UniProt:Q0J7U6 TPR2

chain
  • chain:1-1133
checksum 84E02BA8FF102922
comment
  • FUNCTION Transcriptional corepressor involved in branch formation regulation, presumably by suppressing primary branch formation and promoting secondary branch formation (PubMed:22136599, PubMed:24336200, Ref.7). Required for the cell elongation in the first internode and pollen development (PubMed:22020753). Probable downstream regulator of strigolactones signaling important in axillary meristem maintenance (PubMed:22136599, PubMed:24336200, Ref.7). Acts in auxin signaling and is associated with the regulation of histone deacetylation (PubMed:22136599). Essential for the function of miR172 microRNA and its target genes in regulating panicle development (PubMed:26631749).SUBUNIT Tetramer (PubMed:26601214). Interacts with D53, probably via the EAR motifs (PubMed:24336200). Binds to AP2-1/TOE1, AP2-3/SNB and AP2-2/IDS1 (PubMed:26631749). Interacts with WOX1 (PubMed:24336200, PubMed:25697101, PubMed:26601214, PubMed:26631749). Interacts with MOF1 (PubMed:32680975).SUBCELLULAR LOCATION Expressed in stems and panicles. Detected in roots, seeds, leaves and sheath (PubMed:22020753). Expressed in the meristem and lateral organ primordia (PubMed:22136599).DEVELOPMENTAL STAGE Highest expression in endosperm at 7 days after pollination.DOMAIN The N-terminal TOPLESS domain (TPD) (1-210) binds directly to a 12-amino acid LxLxL EAR motif peptide.DISRUPTION PHENOTYPE Semi-dwarf, with reduced male fertility and shorter panicles with arrested branches and abnormal spikelets.
created [InstanceEdit:5632076] Amarasinghe, Vindhya, 2014-10-28
databaseName UniProt
dbId 5632032
description
  • recommendedName: fullName evidence="15"Protein TOPLESS-RELATED PROTEIN 2 shortName evidence="15"Protein TPR2 alternativeName: fullName evidence="14"Protein ABERRANT SPIKELET AND PANICLE 1 shortName evidence="14"Protein ASP1 alternativeName: fullName evidence="13"Protein LISSENCEPHALY TYPE-1-LIKE 1 shortName evidence="13"OsLIS-L1 shortName evidence="13"Protein LIS-L1 alternativeName: fullName evidence="16"Protein TPL shortName evidence="16"OsTPL alternativeName: fullName evidence="17"Ramosa1 enhancer locus 2 shortName evidence="17"OsREL2 shortName evidence="17"Protein REL2 alternativeName: fullName evidence="16"Topless-like protein
displayName UniProt:Q0J7U6 TPR2
geneName
  • TPR2
  • ASP1
  • LIS-L1
  • REL2
  • TPL
  • Os08g0162100
  • LOC_Os08g06480
  • OsJ_26138
  • P0577B11.132
identifier Q0J7U6
isSequenceChanged false
keyword
  • Nucleus
  • Reference proteome
  • Repeat
  • Transcription
  • Transcription regulation
  • WD repeat
modified [InstanceEdit:9917590] Weiser, Joel, 2024-08-09
name
  • TPR2
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TPR2_ORYSJ
  • Q7EYE2
sequenceLength 1133
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0J7U6