UniProt:Q0J2L7 PP2C68

chain
  • chain:1-358
checksum 4EAAAC406D56A39F
comment
  • FUNCTION Involved in the regulation of abiotic stress responses (PubMed:25886365). Acts as a negative regulator of abscisic acid (ABA) signaling and positive regulator of abiotic stress signaling (PubMed:25886365). May be involved in panicle development (Probable).CATALYTIC ACTIVITY O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphateCATALYTIC ACTIVITY O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphateCOFACTOR Binds 2 magnesium or manganese ions per subunit.SUBCELLULAR LOCATION Localizes predominantly in the nucleus and partially in the cytosol.DEVELOPMENTAL STAGE Expressed transiently during early panicle development.INDUCTION Induced by salt, osmotic and cold stresses (PubMed:23086454, PubMed:25886365). Induced by abscisic acid (ABA) (PubMed:23086454, PubMed:25886365).MISCELLANEOUS Plants overexpressing P2C68 exhibit insensitivity to abscisic acid (ABA), and tolerance to high salt and mannitol stresses during seed germination, root growth and overall seedling growth (PubMed:25886365). At adult stage, P2C68 overexpression leads to high tolerance to salt, mannitol and drought stresses with far better physiological parameters such as water loss, fresh weight, chlorophyll content and photosynthetic potential (PubMed:25886365).SIMILARITY Belongs to the PP2C family.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.
created [InstanceEdit:4415083] Amarasinghe, V, 2013-08-24
databaseName UniProt
dbId 4415043
description
  • recommendedName: fullName evidence="5"Probable protein phosphatase 2C 68 shortName evidence="5"OsPP2C68 ecNumber: 3.1.3.16 alternativeName: fullName evidence="7"OsPP108 alternativeName: fullName evidence="6"Stress-induced protein phosphatase 2C 1 shortName evidence="6"OsSIPP2C1
displayName UniProt:Q0J2L7 PP2C68
geneName
  • PP2C68
  • PP108
  • SIPP2C1
  • Os09g0325700
  • LOC_Os09g15670
  • OsJ_027745
  • P0692F07.24
identifier Q0J2L7
isSequenceChanged false
keyword
  • Cytoplasm
  • Hydrolase
  • Magnesium
  • Manganese
  • Metal-binding
  • Nucleus
  • Protein phosphatase
  • Reference proteome
  • Stress response
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • PP2C68
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • P2C68_ORYSJ
  • A0A0P0XLQ8
  • Q6K3W4
sequenceLength 358
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q0J2L7