UniProt:Q5U9F2 GNA1

chain
  • chain:1-165
checksum 3EB05150B80CDE95
comment
  • FUNCTION Acetyltransferase involved in de novo biosynthesis of UDP-N-acetylglucosamine (UDP-GlcNAc) in roots and is required for maintaining normal root cell shape. UDP-GlcNAc is an essential metabolite that serves as an initial sugar donor for N-glycan synthesis and thus plays an important role in protein and lipid glycosylation.CATALYTIC ACTIVITY D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)BIOPHYSICOCHEMICAL PROPERTIES Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.SUBUNIT Homodimer.SUBCELLULAR LOCATION Highly expressed in the root elongation zone and at lower levels in leaves and grains.DISRUPTION PHENOTYPE Short roots, disruption of microtubules and shrinkage of cells in the root elongation zone.SIMILARITY Belongs to the acetyltransferase family. GNA1 subfamily.
created [InstanceEdit:2960793] D'Eustachio, P, 2013-01-04
databaseName UniProt
dbId 2960776
description
  • recommendedName: Glucosamine 6-phosphate N-acetyltransferase 1 ecNumber evidence="4"2.3.1.4 alternativeName: Glucose-6-phosphate acetyltransferase 1 shortName: OsGNA1 alternativeName: Phosphoglucosamine acetylase 1 alternativeName: Phosphoglucosamine transacetylase 1
displayName UniProt:Q5U9F2 GNA1
geneName
  • GNA1
  • Os09g0488000
  • LOC_Os09g31310
identifier Q5U9F2
isSequenceChanged false
keyword
  • Acyltransferase
  • Endoplasmic reticulum
  • Membrane
  • Reference proteome
  • Transferase
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
name
  • GNA1
referenceDatabase [ReferenceDatabase:2] UniProt
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • GNA1_ORYSJ
  • A0A0N7KR10
sequenceLength 165
species [Species:1250427] Oryza sativa subsp. japonica
url http://purl.uniprot.org/uniprot/Q5U9F2